Compounds > defucogilvocarcin v
Page last updated: 2024-12-07

defucogilvocarcin v

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

defucogilvocarcin V: isolated from Streptomyces arenae 2064; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID133386
CHEMBL ID5206332
MeSH IDM0136681

Synonyms (7)

Synonym
6h-benzo(d)naphtho(1,2-b)pyran-6-one, 8-ethenyl-1-hydroxy-10,12-dimethoxy-
1-hydroxy-10,12-dimethoxy-8-vinyl-6h-benzo(d)naphthol(1,2b)pyran-6-one
gilvocarcin v aglycone
defucogilvocarcin v
80155-95-9
DTXSID40230107
CHEMBL5206332
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID1875263Antibacterial activity against Pseudomonas aeruginosa ATCC 10145 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
AID1875265Antibacterial activity against Candida albicans ATCC 10231 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
AID1875264Antibacterial activity against Escherichia coli ATCC 11775 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
AID1875262Antibacterial activity against methicillin resistant Staphylococcus aureus ATCC 43300 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
AID1875266Antibacterial activity against Candida Candida glabrata ATCC 2001 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
AID1875261Antibacterial activity against Staphylococcus aureus ATCC 6538 by broth microdilution method2022Journal of natural products, 10-28, Volume: 85, Issue:10
Antibacterial Gilvocarcin-Type Aryl-
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (33.33)18.7374
1990's1 (16.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.79

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.79 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.73 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.79)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
cytosine
[no description available]		1.9710aminopyrimidine;
pyrimidine nucleobase;
pyrimidone		Escherichia coli metabolite;
human metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite
ciprofloxacin
Ciprofloxacin: A broad-spectrum antimicrobial carboxyfluoroquinoline.. ciprofloxacin : A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively.		3.5110aminoquinoline;
cyclopropanes;
fluoroquinolone antibiotic;
N-arylpiperazine;
quinolinemonocarboxylic acid;
quinolone antibiotic;
quinolone;
zwitterion		antibacterial drug;
antiinfective agent;
antimicrobial agent;
DNA synthesis inhibitor;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor;
environmental contaminant;
topoisomerase IV inhibitor;
xenobiotic
thymidine
[no description available]		1.9710pyrimidine 2'-deoxyribonucleosideEscherichia coli metabolite;
human metabolite;
metabolite;
mouse metabolite
2-naphthol
2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.		1.9710naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
arnottin i
arnottin I: structure in first source		2.0510
glycosides
[no description available]		2.6830
gilvocarcin v
gilvocarcin V: from Actinomycete DO-38; structure given in first source		3.8230
warfarin
Warfarin: An anticoagulant that acts by inhibiting the synthesis of vitamin K-dependent coagulation factors. Warfarin is indicated for the prophylaxis and/or treatment of venous thrombosis and its extension, pulmonary embolism, and atrial fibrillation with embolization. It is also used as an adjunct in the prophylaxis of systemic embolism after myocardial infarction. Warfarin is also used as a rodenticide.. warfarin : A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.. 4-hydroxy-3-(3-oxo-1-phenylbutyl)-1-benzopyran-2-one : A member of the class of coumarins that is 4-hydroxycoumarin which is substituted at position 3 by a 1-phenyl-3-oxo-1-butyl group.		2.6830benzenes;
hydroxycoumarin;
methyl ketone
gilvocarcin m
gilvocarcin M: from Actinomycete DO-38; structure given in first source		2.4120
ConditionIndicatedRelationship StrengthStudiesTrials