Compounds > d-argininamide, d-phenylalanyl-d-phenylalanyl-d-norleucyl-n-(4-pyridinylmethyl)-
Page last updated: 2024-08-03 11:39:14

d-argininamide, d-phenylalanyl-d-phenylalanyl-d-norleucyl-n-(4-pyridinylmethyl)-

Description

Cross-References

ID SourceID
PubMed CID25030387
SCHEMBL ID4451321
MeSH IDM0577432

Synonyms (17)

Synonym
cr665
cr-665
fe200665
fe-200665
unii-3bx9ug06gg
228546-92-7
3bx9ug06gg ,
cr 665
d-argininamide, d-phenylalanyl-d-phenylalanyl-d-norleucyl-n-(4-pyridinylmethyl)-
fe 200665
SCHEMBL4451321
DTXSID30177395
jnj-38488502
DB05155
Q5425398
HY-P3609
CS-0616401

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials2 (40.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other3 (60.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
acetic acid
1
monocarboxylic acidantimicrobial food preservative;
Daphnia magna metabolite;
food acidity regulator;
protic solvent		2008200816.0medium000100
u 69593
2
monocarboxylic acid amide;
N-alkylpyrrolidine;
organic heterobicyclic compound;
oxaspiro compound		anti-inflammatory agent;
diuretic;
kappa-opioid receptor agonist		2001200819.5high000200
naloxone
1
morphinane alkaloid;
organic heteropentacyclic compound;
tertiary alcohol		antidote to opioid poisoning;
central nervous system depressant;
mu-opioid receptor antagonist		2001200123.0medium000100
oxycodone
2
organic heteropentacyclic compound;
semisynthetic derivative		antitussive;
mu-opioid receptor agonist;
opioid analgesic		2009201313.0high200110
naltrexone
1
cyclopropanes;
morphinane-like compound;
organic heteropentacyclic compound		antidote to opioid poisoning;
central nervous system depressant;
environmental contaminant;
mu-opioid receptor antagonist;
xenobiotic		2001200123.0medium000100
norbinaltorphimine
1
isoquinolines2001200123.0medium000100
guanosine 5'-o-(3-thiotriphosphate)
1
nucleoside triphosphate analogue2008200816.0medium000100
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Ache0
3
2008201912.0high100210
Inflammation0
1
2001200123.0medium000100
Innate Inflammatory Response0
1
2001200123.0medium000100
Pain0
3
2008201912.0high100210

Pharmacokinetics (1)

ArticleYear
A population pharmacokinetic and pharmacodynamic study of a peripheral κ-opioid receptor agonist CR665 and oxycodone.
Clinical pharmacokinetics, , Volume: 52, Issue:2		2013

Dosage (1)

ArticleYear
Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain.
Anesthesiology, , Volume: 111, Issue:3		2009