Assay ID | Title | Year | Journal | Article |
AID506966 | Inhibition of HSP90-mediated antiapoptotic activity in human H69AR cells assessed as induction of PARP cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID395895 | Cytotoxicity against human MCF7 cells | 2009 | Bioorganic & medicinal chemistry, Mar-15, Volume: 17, Issue:6
| Discovery and development of heat shock protein 90 inhibitors. |
AID506961 | Inhibition of HSP90-mediated antiapoptotic activity in human SKI-AC3 cells assessed as increase in caspase-3 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506968 | Inhibition of HSP90-mediated antiapoptotic activity in human WBA cells assessed as induction of PARP cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506584 | Binding affinity to HSP90 in human NCI-H526 cells at 1 uM after 24 hrs by fluorescence polarization assay | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506971 | Inhibition of HSP90-mediated antiapoptotic activity in human WBA cells assessed as increase in caspase-7 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506963 | Inhibition of HSP90-mediated antiapoptotic activity in human H69AR cells assessed as induction of caspase-3 cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506967 | Inhibition of HSP90-mediated antiapoptotic activity in human SKI-AC3 cells assessed as induction of PARP cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506960 | Inhibition of HSP90-mediated antiapoptotic activity in human H69AR cells assessed as increase in caspase-3 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506969 | Inhibition of HSP90-mediated antiapoptotic activity in human H69AR cells assessed as increase in caspase-7 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID395896 | Inhibition of Hsp90 | 2009 | Bioorganic & medicinal chemistry, Mar-15, Volume: 17, Issue:6
| Discovery and development of heat shock protein 90 inhibitors. |
AID506585 | Inhibition of HSP90-mediated proliferation of human NCI-H526 cells at 1 uM after 96 hrs by sulforhodamine B assay | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506964 | Inhibition of HSP90-mediated antiapoptotic activity in human SKI-AC3 cells assessed as induction of caspase-3 cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506965 | Inhibition of HSP90-mediated antiapoptotic activity in human WBA cells assessed as induction of caspase-3 cleavage at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506962 | Inhibition of HSP90-mediated antiapoptotic activity in human WBA cells assessed as increase in caspase-3 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
AID506970 | Inhibition of HSP90-mediated antiapoptotic activity in human SKI-AC3 cells assessed as increase in caspase-7 activity at 10 uM after 48 hrs by Western blot analysis | 2007 | Nature chemical biology, Aug, Volume: 3, Issue:8
| Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |