Compounds > cribrostatin 4
Page last updated: 2024-12-11

cribrostatin 4

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

cribrostatin 4: from Cribrochalina species; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9861633
CHEMBL ID497275
SCHEMBL ID7669690
MeSH IDM0368839

Synonyms (3)

Synonym
CHEMBL497275
cribrostatin 4
SCHEMBL7669690
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (22)

Assay IDTitleYearJournalArticle
AID381307Antibacterial activity against Micrococcus luteus Presque Isle 456 by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381321Antibacterial activity against Stenotrophomonas maltophilia ATCC 13637 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381033Growth inhibition of human NCI-H460 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381030Growth inhibition of human OVCAR-3 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381317Antibacterial activity against invasive Streptococcus pneumoniae isolate by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381031Growth inhibition of human SF295 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381037Growth inhibition of mouse P388 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381325Antibacterial activity against penicillin-resistant Neisseria gonorrhoeae isolate by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381034Growth inhibition of human KM20L2 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381306Antifungal activity against Cryptococcus neoformans ATCC 90112 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381313Antibacterial activity against Bacillus subtilis Presque Isle 620 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381323Antibacterial activity against Enterobacter cloacae ATCC 13047 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381324Antibacterial activity against Neisseria gonorrhoeae ATCC 49226 by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381319Antibacterial activity against group A Streptococcus isolate by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381315Antibacterial activity against Streptococcus pneumoniae ATCC 6303 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381310Antibacterial activity against Staphylococcus aureus ATCC 29213 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381028Growth inhibition of human BXPC3 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381322Antibacterial activity against Escherichia coli ATCC 25922 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381311Antibacterial activity against Enterococcus faecalis ATCC 29212 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381036Growth inhibition of human DU145 cells2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381316Antibacterial activity against penicillin-resistant Streptococcus pneumoniae isolate by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
AID381304Antifungal activity against Candida albicans ATCC 90028 at 100 ug/disk by disk diffusion method2000Journal of natural products, Jun, Volume: 63, Issue:6
Antineoplastic agents 430. Isolation and structure of cribrostatins 3, 4, and 5 from the republic of maldives cribrochalina species.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's1 (12.50)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
quinone
benzoquinone : The simplest members of the class of benzoquinones, consisting of cyclohexadiene which is substituted by two oxo groups.. 1,4-benzoquinone : The simplest member of the class of 1,4-benzoquinones, obtained by the formal oxidation of hydroquinone to the corresponding diketone. It is a metabolite of benzene.. quinone : Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included).		2.11101,4-benzoquinonescofactor;
human xenobiotic metabolite;
mouse metabolite
piperazine
[no description available]		2.1110azacycloalkane;
piperazines;
saturated organic heteromonocyclic parent		anthelminthic drug
ecteinascidin 743
[no description available]		7.5220acetate ester;
azaspiro compound;
bridged compound;
hemiaminal;
isoquinoline alkaloid;
lactone;
organic heteropolycyclic compound;
organic sulfide;
oxaspiro compound;
polyphenol;
tertiary amino compound		alkylating agent;
angiogenesis modulating agent;
anti-inflammatory agent;
antineoplastic agent;
marine metabolite
3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione
3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione: isolated from Streptomyces griseoluteus fermentation broth; RN given refers to cpd without isomeric designation; structure		2.0610
ConditionIndicatedRelationship StrengthStudiesTrials
Benign Neoplasms
[description not available]		02.4110
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.		02.4110