corchoionoside C: structure given in first source; from leaves of Corchorus olitorius [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Corchorus | genus | A plant genus of the family TILIACEAE. Members contain cycloartane saponins and CARDENOLIDES.[MeSH] | Malvaceae | The mallow family of the order MALVALES, subclass Dilleniidae, class Magnoliopsida. The common names of hollyhock and mallow are used for several genera of Malvaceae.[MeSH] |
| Corchorus olitorius | species | [no description available] | Malvaceae | The mallow family of the order MALVALES, subclass Dilleniidae, class Magnoliopsida. The common names of hollyhock and mallow are used for several genera of Malvaceae.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 10317980 |
| CHEMBL ID | 444196 |
| MeSH ID | M0275568 |
| Synonym |
|---|
| corchoionoside c |
| CHEMBL444196 |
| 6s,9s-roseoside |
| 185414-25-9 |
| (6s,9s)-roseoside |
| (4s)-4-hydroxy-3,5,5-trimethyl-4-[(e,3s)-3-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxybut-1-enyl]cyclohex-2-en-1-one |
| DTXSID101316706 |
| AKOS040761526 |
| FS-10509 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID471992 | Inhibition of osteoclastogenesis in RANKL and M-CSF-stimulated mouse BMDM cells after 4 days by TRAP assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Inhibitors of osteoclast formation from rhizomes of Cibotium barometz. |
| AID471993 | Cytotoxicity against RANKL and M-CSF-stimulated mouse BMDM cells at 100 to 200 uM after 72 hrs by MTS-cell titer assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Inhibitors of osteoclast formation from rhizomes of Cibotium barometz. |
| AID1193988 | Inhibition of LPS-induced IL-12 p40 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Chemical constituents from Kandelia candel with their inhibitory effects on pro-inflammatory cytokines production in LPS-stimulated bone marrow-derived dendritic cells (BMDCs). |
| AID1193989 | Inhibition of LPS-induced IL-6 production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Chemical constituents from Kandelia candel with their inhibitory effects on pro-inflammatory cytokines production in LPS-stimulated bone marrow-derived dendritic cells (BMDCs). |
| AID614278 | Antiinflammatory activity in rat HAPI cells assessed as inhibition of LPS-induced iNOS mRNA expression at 50 uM treated 30 mins before LPS challenge measured after 6 hrs by RT-PCR analysis | 2011 | Bioorganic & medicinal chemistry, Sep-15, Volume: 19, Issue:18 | Inhibitory effects of chalcone glycosides isolated from Brassica rapa L. 'hidabeni' and their synthetic derivatives on LPS-induced NO production in microglia. |
| AID1654523 | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 6.25 to 100 uM after 24 hrs by EZ-Cytox cell viability assay | |||
| AID1193990 | Inhibition of LPS-induced TNF-alpha production in wild-type C57BL/6 mouse BMDC pretreated with compound for 1 hr before LPS treatment measured 16 hrs by ELISA | 2015 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 25, Issue:7 | Chemical constituents from Kandelia candel with their inhibitory effects on pro-inflammatory cytokines production in LPS-stimulated bone marrow-derived dendritic cells (BMDCs). |
| AID471989 | Inhibition of osteoclastogenesis in RANKL and M-CSF-stimulated mouse BMDM cells at 200 uM after 4 days by TRAP assay | 2009 | Journal of natural products, Sep, Volume: 72, Issue:9 | Inhibitors of osteoclast formation from rhizomes of Cibotium barometz. |
| AID410705 | Inhibition of leukotriene release in ICR mouse BMCMC at 100 mM after 6 hrs by ELISA | 2009 | Bioorganic & medicinal chemistry, Jan-01, Volume: 17, Issue:1 | A simple synthesis of four stereoisomers of roseoside and their inhibitory activity on leukotriene release from mice bone marrow-derived cultured mast cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.63) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||