codorphone: analgesic activity in range of morphine & pentazocine but with no physical dependence caused in rats; RN given refers to parent cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
ID Source | ID |
---|---|
PubMed CID | 5361887 |
CHEMBL ID | 2110790 |
SCHEMBL ID | 488917 |
MeSH ID | M0084901 |
Synonym |
---|
codorphone |
morphinan-6-one, 17-cyclopropylmethyl-4,5-epoxy-8-ethyl-3-methoxy-, (5alpha,8beta)- |
conorfone |
conorphone |
9h58696d23 , |
conorfonum [inn-latin] |
unii-9h58696d23 |
(5r,8r,9r,13s,14r)-n-cyclopropylmethyl-4,5-epoxy-8-ethyl-3-methoxy-6-morphinanon |
conorfonum |
72060-05-0 |
conorfone [inn] |
conorfona |
17-(cyclopropylmethyl)-4,5alpha-epoxy-8beta-ethyl-3-methoxymorphinan-6-one |
conorfona [inn-spanish] |
17-(cyclopropylmethyl)-4,5.alpha.-epoxy-8.beta.-ethyl-3-methoxymorphinan-6-one |
morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-8-ethyl-3-methoxy-, (5.alpha.,8.beta.)- |
SCHEMBL488917 |
CHEMBL2110790 |
conorfone; conorphone; tr 5109 |
DTXSID501016499 |
(4r,4ar,5s,7ar,12bs)-3-(cyclopropylmethyl)-5-ethyl-9-methoxy-1,2,4,4a,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one |
Excerpt | Reference | Relevance |
---|---|---|
" The compound appeared to be well absorbed in the three species." | ( Disposition and metabolism of codorphone in the rat, dog, and man. Evans, JV; Helms, RJ; Leeling, JL; Ryerson, BA, ) | 0.42 |
Excerpt | Relevance | Reference |
---|---|---|
" To illustrate the usefulness of this methodology, a urine sample obtained from a dog that had been dosed with codorphone was analyzed by gas chromatography mass spectrometry, and the metabolites were identified by comparison to the mass spectra of the synthetic derivatives." | ( Methodology for the identification of the urinary metabolites of the analgesic-narcotic antagonist, codorphone, by gas chromatography mass spectrometry. Evans, JV; Helms, RJ; Leeling, JL, 1982) | 0.69 |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 2 (66.67) | 18.7374 |
1990's | 1 (33.33) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 6 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |