cmp-deaminoneuraminic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonate(2-) : A nucleotide-sugar oxoanion obtained by deprotonation of the carboxylic acid and phosphate functions of CMP-3-deoxy-D-glycero-beta-D-galacto-nonulosonic acid; major species at pH 7.3. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID Source	ID
PubMed CID	90658820
CHEBI ID	90989
MeSH ID	M0212768

Synonyms (14)

Synonym
cmp-deaminoneuraminic acid
cmp-3-deoxy-d-glycero-d-galacto-nononic acid
cmp-3-deoxy-d-glycero-d-galacto-nonulosonate
cmp-deaminoneuraminate
cmp-3-deoxy-d-glycero-d-galacto-non-2-ulopyranosonate
cmp-3-deoxy-d-glycero-d-galacto-nonulosonic acid
cmp-3-deoxy-d-glycero-d-galacto-nononate
cmp-kdn(2-)
cmp-beta-3-deoxy-d-glycero-beta-d-galacto-non-2-ulopyranosonate
CHEBI:90989
cmp-3-deoxy-d-glycero-beta-d-galacto-nononate(2-)
cmp-3-deoxy-d-glycero-beta-d-galacto-nonulosonate(2-)
SFLGTPJBQWRIMH-ZBOJUINDSA-L
Q27162990

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
nucleotide-sugar oxoanion	Any nucleotide-sugar in which one or more of the diphosphate OH groups has been deprotonated.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Pathways (2)

Pathway	Proteins	Compounds
superpathway of CMP-sialic acids biosynthesis	14	60
CMP-2-keto-3-deoxy-D-glycero-D-galacto-nononate biosynthesis	4	19

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	4 (57.14)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (14.29)	24.3611
2020's	2 (28.57)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
galactose galactopyranose : The pyranose form of galactose.	1.98	1	D-galactose; galactopyranose	Escherichia coli metabolite; mouse metabolite
cytidine monophosphate Cytidine Monophosphate: Cytidine (dihydrogen phosphate). A cytosine nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.. cytidine 5'-monophosphate : A pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.	3.41	7	cytidine 5'-phosphate; pyrimidine ribonucleoside 5'-monophosphate	Escherichia coli metabolite; human metabolite; mouse metabolite
cytidine triphosphate Cytidine Triphosphate: Cytidine 5'-(tetrahydrogen triphosphate). A cytosine nucleotide containing three phosphate groups esterified to the sugar moiety.	1.98	1	cytidine 5'-phosphate; pyrimidine ribonucleoside 5'-triphosphate	Escherichia coli metabolite; mouse metabolite
transferrin Transferrin: An iron-binding beta1-globulin that is synthesized in the LIVER and secreted into the blood. It plays a central role in the transport of IRON throughout the circulation. A variety of transferrin isoforms exist in humans, including some that are considered markers for specific disease states.	1.99	1
3-deoxyglycero-galacto-nonulosonic acid 3-deoxyglycero-galacto-nonulosonic acid: deaminated neuraminic acid from rainbow trout; structure given in first source	1.98	1	L-alpha-D-Hepp-(1->7)-L-alpha-D-Hepp-(1->3)-L-alpha-D-Hepp-(1->5)-alpha-Kdo
n-acetylneuraminic acid N-Acetylneuraminic Acid: An N-acyl derivative of neuraminic acid. N-acetylneuraminic acid occurs in many polysaccharides, glycoproteins, and glycolipids in animals and bacteria. (From Dorland, 28th ed, p1518). N-acetylneuraminic acid : An N-acylneuraminic acid where the N-acyl group is specified as acetyl.	3	4	N-acetylneuraminic acids	antioxidant; bacterial metabolite; EC 3.2.1.18 (exo-alpha-sialidase) inhibitor; human metabolite; mouse metabolite
n-acetyllactosamine N-acetyllactosamine: RN given refers to D-isomer. N-acetyllactosamine : A beta-D-galactopyranosyl-(1->4)-N-acetyl-D-glucosamine having beta-configuration at the reducing end anomeric centre.	1.99	1	beta-D-Galp-(1->4)-D-GlcpNAc
cytidine monophosphate n-acetylneuraminic acid Cytidine Monophosphate N-Acetylneuraminic Acid: A nucleoside monophosphate sugar which donates N-acetylneuraminic acid to the terminal sugar of a ganglioside or glycoprotein.. CMP-N-acetyl-beta-neuraminic acid : A nucleotide sugar used as a donor by glycosyltransferases for the synthesis of sugar chains	1.99	1	CMP-N-acyl-beta-neuraminic acid	mouse metabolite
glycosides [no description available]	2	1
hymecromone Hymecromone: A coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.	2	1	hydroxycoumarin	antineoplastic agent; hyaluronic acid synthesis inhibitor

Condition	Indicated	Relationship Strength	Studies	Trials
Neisseria gonorrhoeae Infection [description not available]	0	2.25	1	0
Gonorrhea Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879.	0	2.25	1	0

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