AID1671813 | Anticancer activity against human DU-145 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID664751 | Neuroprotective activity in rat PC12 cells assessed as inhibition of serum starvation-induced cell death after 24 hrs by MTT assay | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4
| Carbazole alkaloids from the stems of Clausena lansium. |
AID1671811 | Anticancer activity against human MCF7 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID1671812 | Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID1671818 | Cytotoxicity against HEK293 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID664750 | Neuroprotective activity in rat PC12 cells assessed as inhibition of SNP-induced cell death at 10 uM incubated 24 hrs post SNP-challenge for 24 hrs by MTT assay | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4
| Carbazole alkaloids from the stems of Clausena lansium. |
AID1348564 | Cytoprotective activity against H2O2-induced damage in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay (Rvb = 70.1 +/- 3.7%) | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Pyrano[3,2-a]carbazole alkaloids as effective agents against ischemic stroke in vitro and in vivo. |
AID1671815 | Anticancer activity against human HepG2 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID1348566 | Cytoprotective activity against oxygen-glucose deprivation/reoxygenation-induced damage in rat PC12 cells assessed as cell viability at 10 uM after 24 hrs by MTT assay (Rvb = 70 +/- 5.1%) | 2018 | European journal of medicinal chemistry, Jan-01, Volume: 143 | Pyrano[3,2-a]carbazole alkaloids as effective agents against ischemic stroke in vitro and in vivo. |
AID664749 | Neuroprotective activity in rat PC12 cells assessed as inhibition of amyloid beta(25 to 35)-induced cell death at 10 uM incubated 48 hrs post amyloid beta-challenge for 24 hrs by MTT assay | 2012 | Journal of natural products, Apr-27, Volume: 75, Issue:4
| Carbazole alkaloids from the stems of Clausena lansium. |
AID1671814 | Anticancer activity against human PC-3 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID1671816 | Anticancer activity against human DLD-1 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
AID1671817 | Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay | 2019 | European journal of medicinal chemistry, Apr-01, Volume: 167 | Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of Akt/mTOR in breast cancer cells. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |