Compounds > cinnamoyl chloride
Page last updated: 2024-12-11

cinnamoyl chloride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

cinnamoyl chloride: RN given refers to cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5354261
SCHEMBL ID37935
MeSH IDM0113554

Synonyms (59)

Synonym
unii-04l46s032w
04l46s032w ,
2-propenoyl chloride, 3-phenyl-, (e)-
LS-13582
(e)-3-phenyl-acryloyl chloride
.beta.-phenylacryloyl chloride
102-92-1
nsc-4683
2-propenoyl chloride, 3-phenyl-
cinnamic chloride
cinnamoylchloride
cinnamic acid chloride
cinnamoyl chloride
nsc4683
3-phenyl-2-propenoyl chloride
cinnamoyl chloride, 98%
3-phenylprop-2-enoyl chloride
(e)-3-phenylprop-2-enoyl chloride
17082-09-6
P0133
trans-3-phenylacryloyl chloride
AKOS000121270
A800646
(e)-3-phenyl-2-propenoyl chloride
nsc 4683
einecs 203-065-5
beta-phenylacryloyl chloride
BBL011393
(2e)-3-phenylprop-2-enoyl chloride
STL146496
trans-cinnamoyl chloride
AM20060479
phenylacryloylchloride
[(2e)-3-phenylprop-2-enoyl]chloride
trans-cinnamoylchloride
(2e)-3-phenylacryloyl chloride
SCHEMBL37935
benzylideneacetyl chloride
cinnamoyl chloride [mi]
trans-cinnamic acid chloride
(e)-cinnamoyl chloride
2-propenoyl chloride, 3-phenyl-, (2e)-
3-phenylacryloyl chloride
Q-200858
F2190-0089
CS-0006860
6-[bis[bis(isopropyl)amino]acetate]-d-gluconicacid
Q204169
3-amino-4-morpholin-4-yl-benzoicacidethylester
3L-308S
mfcd00000732
D91905
trans-3-phenylacryloyl chlorid
trans-cinnamoyl chloride,97%
A881990
DTXSID401312860
2-propenoyl chloride,3-phenyl-, (2e)-
EN300-19598
EN300-248477
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (22.22)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 34.35

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index34.35 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.32 (4.65)
Search Engine Demand Index44.85 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (34.35)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
quinacrine
Quinacrine: An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.. quinacrine : A member of the class of acridines that is acridine substituted by a chloro group at position 6, a methoxy group at position 2 and a [5-(diethylamino)pentan-2-yl]nitrilo group at position 9.		2.1110acridines;
aromatic ether;
organochlorine compound;
tertiary amino compound		antimalarial;
EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor
chlorine
chloride : A halide anion formed when chlorine picks up an electron to form an an anion.		2.1110halide anion;
monoatomic chlorine		cofactor;
Escherichia coli metabolite;
human metabolite
2-butynedioic acid
2-butynedioic acid: RN given refers to parent cpd. butynedioic acid : An acetylenic compound that is acetylene in which the hydrogens are replaced by carboxy groups.		2.0710acetylenic compound;
C4-dicarboxylic acid
1-propanol
1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.. propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.		2.3620propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
1-methylimidazole
1-methyl-1H-imidazole : A 1H-imidazole having a methyl substituent at the N-1 position.		2.3620imidazoles
4-aminopyridine
[no description available]		2.3620aminopyridine;
aromatic amine		avicide;
orphan drug;
potassium channel blocker
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.		2.1110aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
cyanides
Cyanides: Inorganic salts of HYDROGEN CYANIDE containing the -CN radical. The concept also includes isocyanides. It is distinguished from NITRILES, which denotes organic compounds containing the -CN radical.. cyanides : Salts and C-organyl derivatives of hydrogen cyanide, HC#N.. isocyanide : The isomer HN(+)#C(-) of hydrocyanic acid, HC#N, and its hydrocarbyl derivatives RNC (RN(+)#C(-)).. cyanide : A pseudohalide anion that is the conjugate base of hydrogen cyanide.		7.0710pseudohalide anionEC 1.9.3.1 (cytochrome c oxidase) inhibitor
benzoyl chloride
benzoyl chloride: potential carcinogens in manufacturing process. benzoyl chloride : An acyl chloride consisting of benzene in which a hydrogen is replaced by an acyl chloride group. It is an important chemical intermediate for the manufacture of other chemicals, dyes, perfumes, herbicides and pharmaceuticals.		2.0710acyl chloride;
benzenes		carcinogenic agent
propylene
propylene: structure		2.0710alkene;
gas molecular entity		refrigerant;
xenobiotic
alpha-aminopyridine
alpha-aminopyridine: RN given refers to parent cpd; structure in Merck Index, 9th ed, #485. aminopyridine : Compounds containing a pyridine skeleton substituted by one or more amine groups.		2.3620
4-dimethylaminopyridine
4-dimethylaminopyridine: catalyst for acetylation of hydroxy cpds; structure		2.3620dialkylarylamine;
tertiary amino compound
alkenes
[no description available]		2.0710
glucose, (beta-d)-isomer
beta-D-glucose : D-Glucopyranose with beta configuration at the anomeric centre.. (1->4)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->4) linkages.. (1->3)-beta-D-glucan : A beta-D-glucan in which the glucose units are connected by (1->3) linkages.		2.0810D-glucopyranoseepitope;
mouse metabolite
2-vinylfuran
2-vinylfuran: has antimicrobial activity		2.0710
glycosides
[no description available]		2.0810
cinnamic anhydride
cinnamic anhydride: RN given refers to cpd without isomeric designation		2.3620
ConditionIndicatedRelationship StrengthStudiesTrials
Acute Confusional Senile Dementia
[description not available]		02.2510
Idiopathic Parkinson Disease
[description not available]		02.2510
Alzheimer Disease
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)		02.2510
Parkinson Disease
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)		02.2510