| AID1810210 | Induction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse microglia neurons assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810228 | Negative allosteric modulation of mouse GABA receptor in mouse peptidergic nociceptive DRG neurons assessed as inhibition of KCl-induced response at 10 uM | | | |
| AID1810239 | Negative allosteric modulation of human GABA receptor expressed in mouse DRG neurons assessed as inhibition of 340 nM GABA-induced responses at 0.5 uM using c-LTMRS | | | |
| AID1810220 | Negative allosteric modulation activity at human GABAA alpha1beta3gamma2 stably expressed in HEK cells by whole cell patch clamp method | | | |
| AID1810234 | Antinociceptive activity in C57BL6 mouse model of inflammatory pain assessed as total number of responses during second phase at 2 to 50 mg/kg, ip administered by formalin test | | | |
| AID1810231 | Antinociceptive activity in mouse assessed as total number of responses at 2 to 50 mg/kg, ip by by Von Frey test | | | |
| AID1810236 | Induction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse DRG other neuron subtype assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810233 | Anxiolytic activity in restraint stress induced anxiety mouse model assessed as total number of responses at 2 to 50 mg/kg, ip administered measured after 5 mins by open field test | | | |
| AID1810221 | Negative allosteric modulation activity at human GABAA alpha2beta3gamma2 stably expressed in HEK cells by whole cell patch clamp method | | | |
| AID1810245 | Negative allosteric modulation of mouse GABA receptor in mouse C-low-threshold mechanoreceptive DRG neurons assessed as inhibition of KCl-induced response at 10 uM | | | |
| AID1810212 | Induction of cytosolic calcium ion concentration in mouse microglia cells at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810211 | Reduction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse microglia neurons assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810215 | Induction of cytosolic calcium ion concentration in mouse peptidergic nociceptive DRG neuron at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810226 | Negative allosteric modulation of human GABA receptor expressed in mouse DRG neurons assessed as inhibition of 500 nM GABA-induced response at 0.5 uM | | | |
| AID1810235 | Anxiolytic activity in restraint stress induced anxiety mouse model assessed as total number of responses at 2 to 50 mg/kg, ip administered measured after 5 mins by plus maze test | | | |
| AID1810224 | Negative allosteric modulation activity at human GABAA alpha5beta3gamma2 stably expressed in HEK cells by patch clamp method | | | |
| AID1810229 | Negative allosteric modulation of mouse GABA receptor in mouse non-peptidergic nociceptive DRG neurons assessed as inhibition of KCl-induced response at 10 uM | | | |
| AID1810230 | Negative allosteric modulation of mouse GABA receptor in mouse C-low-threshold mechanoreceptive DRG neurons assessed as inhibition of KCl-induced response at 40 uM | | | |
| AID1810218 | Induction of cytosolic calcium ion concentration in mouse non-peptidergic nociceptive DRG neuron at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810246 | Negative allosteric modulation of mouse GABA receptor in mouse DRG neurons assessed as inhibition of KCl-induced response at 10 uM using cold thermosensors | | | |
| AID1810225 | Negative allosteric modulation of human GABA receptor expressed in HEK cells assessed as inhibition of GABA-induced current in presence of EC20 concentration of GABA by patch clamp method | | | |
| AID1810223 | Negative allosteric modulation activity at human GABAA alpha4beta3gamma2 stably expressed in HEK cells by patch clamp method | | | |
| AID1810237 | Reduction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse DRG other neuron subtype assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810219 | Negative allosteric modulation activity at human GABAA alpha1beta1gamma2 stably expressed in HEK cells by whole cell patch clamp method | | | |
| AID1810217 | Reduction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse non-peptidergic nociceptive DRG neuron assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810222 | Negative allosteric modulation activity at human GABAA alpha3beta3gamma2 stably expressed in HEK cells by whole cell patch clamp method | | | |
| AID1810227 | Negative allosteric modulation of human GABA receptor expressed in mouse DRG neurons assessed as inhibition of 340 nM GABA-induced responses at 0.5 uM using nociceptor | | | |
| AID1810238 | Induction of cytosolic calcium ion concentration in mouse DRG other neuron subtype at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810216 | Induction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse non-peptidergic nociceptive DRG neuron assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810213 | Induction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse peptidergic nociceptive DRG neuron assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810214 | Reduction of ATP and Kcl-induced increase in cytosolic Ca2+ ion concentration mouse peptidergic nociceptive DRG neuron assessed as neuron population at 10 uM measured after 1 hr by Fura2AM dye based fluorescence microscopic analysis | | | |
| AID1810240 | Negative allosteric modulation of human GABA receptor expressed in mouse DRG neurons assessed as inhibition of 340 nM GABA-induced responses at 0.5 uM using cold thermo-sensors | | | |
| AID1810232 | Antinociception activity in mouse model assessed as reduction in thermal hypersensitivity at 2 to 50 mg/kg, ip by hot plate test | | | |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |