chelidonic acid
Chelidonic acid is a naturally occurring organic compound with the formula C7H4O6. It is a white crystalline solid that is soluble in water. Chelidonic acid is found in a variety of plants, including the greater celandine (Chelidonium majus) from which it derives its name. It has been reported to have various biological activities, including antimicrobial, anti-inflammatory, and antioxidant effects. Chelidonic acid is also used as a reagent in organic synthesis and as an indicator in analytical chemistry. Studies on chelidonic acid are conducted to explore its potential pharmacological applications, understand its biosynthesis in plants, and investigate its role in plant defense mechanisms. Chelidonic acid has also been investigated for its potential as a natural pesticide.'
Cross-References
ID Source | ID |
---|---|
PubMed CID | 7431 |
CHEBI ID | 3586 |
SCHEMBL ID | 70569 |
MeSH ID | M0135627 |
Synonyms (69)
Synonym |
---|
c7h4o6 |
BB 0221249 |
4-oxo-pyran-2,6-dicarboxylic acid |
.gamma.-pyrone-2,6-dicarboxylic acid |
wln: t6o dvj bvq fvq |
jervaic acid |
compound xi* (cherry and hageman) |
nsc3979 , |
jervasic acid |
4-oxo-1,6-dicarboxylic acid |
jerva acid |
compound xi* |
nsc-3979 |
2,6-dicarboxyl-4-pyrone |
4h-pyran-2, 4-oxo- |
TIMTEC1_001281 |
ai3-19253 |
gamma-pyrone-2,6-dicarboxylic acid |
4h-pyran-2,6-dicarboxylic acid, 4-oxo- |
4-oxo-1,4-pyran-2,6-dicarboxylic acid |
nsc 3979 |
einecs 202-749-0 |
brn 0163607 |
4-oxopyran-2,6-dicarboxylic acid |
4-oxo-4h-pyran-2,6-dicarboxylic acid |
C08476 |
chelidonic acid , |
99-32-1 |
chelidonic acid, 98% |
NCGC00174597-01 |
HMS1537K05 |
C0955 |
AKOS003368630 |
pbaydyuzosnjgu-uhfffaoysa- |
inchi=1/c7h4o6/c8-3-1-4(6(9)10)13-5(2-3)7(11)12/h1-2h,(h,9,10)(h,11,12) |
STK735535 |
A19372 |
4-oxo-4h-pyran-2,6-dicarboxylicacid |
t33u4w5k6o , |
5-18-08-00646 (beilstein handbook reference) |
unii-t33u4w5k6o |
BP-12076 |
FT-0623586 |
AR-360/40172582 |
chelidonic acid [mi] |
HLD , |
S5579 |
2,6-dicarboxy-4-pyrone |
SCHEMBL70569 |
CHEBI:3586 |
DS-1596 |
mfcd00006577 |
DTXSID30243928 , |
chelidonic acid, analytical standard |
chelidonic acid, purum, anhydrous, >=98.0% (t) |
chelidonsaure |
CS-W022229 |
HY-W041489 |
Q908483 |
BBL037230 |
HMS3886K12 |
AMY36600 |
y-pyrone-2,6-dicarboxylic acid |
CCG-266462 |
chelidonic acid (not validated) |
EN300-82795 |
dtxcid60166419 |
SY031174 |
Z1238543360 |
Research Excerpts
Overview
Chelidonic acid (CA) is a γ-pyrone which is contained in the rhizome of Chelidonium majus L.
Excerpt | Reference | Relevance |
---|---|---|
"Chelidonic acid (CA) is a γ-pyrone which is contained in the rhizome of Chelidonium majus L. " | ( Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells. Chung, WS; Kim, HL; Kim, SJ; Kim, SS; Shin, HJ; Um, JY, 2011) | 2.13 |
Drug Classes (2)
Class | Description |
---|---|
carbonyl compound | Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. |
pyrans | |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (2)
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (18)
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 7 (38.89) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (5.56) | 29.6817 |
2010's | 10 (55.56) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 29.29
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (29.29) All Compounds (24.57) |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 18 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |