Page last updated: 2024-11-12
carboxyibuprofen
Description
carboxyibuprofen: major urinary metabolite of ibuprofen; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
carboxyibuprofen : A dicarboxylic acid that is ibuprofen in which one of the methyl groups in the isobutyl portion has been converted to the corresponding carboxylic acid. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
Synonyms (28)
Synonym |
3-[4-(1-carboxyethyl)phenyl]-2-methylpropanoic acid |
CHEBI:133199 |
ibuprofen cooh |
2,4'-(2-carboxypropyl)phenylpropionic acid |
15935-54-3 |
carboxyibuprofen |
2-(4-(2-carboxypropyl)phenyl)propionic acid |
unii-2ri5xr466k |
benzenepropanoic acid, 4-(1-carboxyethyl)-alpha-methyl- |
2ri5xr466k , |
benzeneacetic acid, 4-(2-carboxypropyl)-alpha-methyl- |
FT-0670259 |
2-[4-(2-carboxypropyl)phenyl]propionic acid |
benzenepropanoic acid, 4-(1-carboxyethyl)-.alpha.-methyl- |
benzeneacetic acid, 4-(2-carboxypropyl)-.alpha.-methyl- |
CHEMBL3544650 |
carboxyibuprofen, vetranal(tm), analytical standard |
AKOS030255447 |
J-009596 |
ibuprofen carboxylic acid |
FT-0670260 |
4-(2-carboxypropyl)-alpha-methyl-benzeneacetic acid |
DTXSID401016127 |
Q27255512 |
benzenepropanoic acid, 4-(1-carboxyethyl)-?-methyl- (9ci); 2,4'-(2-carboxypropyl)phenylpropionic acid; 2-[4-(2-carboxypropyl)phenyl]propionic acid; 4-(2-carboxypropyl)-?-methylbenzeneacetic acid; carboxyibuprofen; ibuprofen cooh |
3-(4-(1-carboxyethyl)phenyl)-2-methylpropanoic acid |
4-(1-carboxyethyl)-alpha-methyl-benzenepropanoic acid |
F77092 |
Roles (1)
Role | Description |
drug metabolite | null |
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (1)
Class | Description |
dicarboxylic acid | Any carboxylic acid containing two carboxy groups. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Research
Studies (8)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (37.50) | 18.2507 |
2000's | 1 (12.50) | 29.6817 |
2010's | 4 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 24.45
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 24.45 (24.57) | Research Supply Index | 2.20 (2.92) | Research Growth Index | 5.01 (4.65) | Search Engine Demand Index | 23.28 (26.88) | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 8 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |