Assay ID | Title | Year | Journal | Article |
AID95607 | Concentration of the Antiproliferative compound required for the 50% inhibition of Growth against K562 cells | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
AID342522 | Inhibition of human IMP dehydrogenase 1 | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. |
AID303356 | Antiproliferative activity against human K562 cells after 72 hrs | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. |
AID1060476 | Antiproliferative activity against human HeLa cells | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| NAD-based inhibitors with anticancer potential. |
AID580127 | Antiproliferative activity against human K562 cells after 72 hrs by MTS assay | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5
| Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. |
AID580128 | Inhibition of human IMPDH1 by Spectrophotometry | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5
| Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. |
AID1060470 | Inhibition of IMPDH1 (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| NAD-based inhibitors with anticancer potential. |
AID492854 | Inhibition of N-terminal His-tagged Mycobacterium tuberculosis H37Rv IMPDH | 2010 | Journal of medicinal chemistry, Jun-24, Volume: 53, Issue:12
| Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis. |
AID268955 | Inhibition of human IMPDH2 | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16
| Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase. |
AID580126 | Inhibition of human IMPDH2 by Spectrophotometer | 2011 | Bioorganic & medicinal chemistry, Mar-01, Volume: 19, Issue:5
| Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain. |
AID1060471 | Inhibition of IMPDH2 (unknown origin) | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| NAD-based inhibitors with anticancer potential. |
AID303351 | Inhibition of human IMPDH type 1 | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. |
AID268954 | Inhibition of human IMPDH1 | 2006 | Journal of medicinal chemistry, Aug-10, Volume: 49, Issue:16
| Novel methylenephosphophosphonate analogues of mycophenolic adenine dinucleotide. Inhibition of inosine monophosphate dehydrogenase. |
AID95472 | Compound effect on differentiation of K562 cells, % of benzidine positive cells at 1.6 uM | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
AID342523 | Inhibition of human IMP dehydrogenase 2 | 2008 | Bioorganic & medicinal chemistry, Aug-01, Volume: 16, Issue:15
| Bis(sulfonamide) isosters of mycophenolic adenine dinucleotide analogues: inhibition of inosine monophosphate dehydrogenase. |
AID92749 | Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II) | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
AID92608 | Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 1 (IMPDH type I) | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
AID303352 | Inhibition of human IMPDH type 2 | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. |
AID1060475 | Antiproliferative activity against human K562 cells | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| NAD-based inhibitors with anticancer potential. |
AID95469 | Compound effect on differentiation of K562 cells, % of benzidine positive cells at 1.0 uM | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Novel mycophenolic adenine bis(phosphonate) analogues as potential differentiation agents against human leukemia. |
AID1060473 | Antiproliferative activity against human HT-29 cells | 2014 | Bioorganic & medicinal chemistry letters, Jan-01, Volume: 24, Issue:1
| NAD-based inhibitors with anticancer potential. |
AID1797841 | IMPDH Type 2 Enzyme Assay from Article 10.1021/jm070568j: \\Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues.\\ | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. |
AID1797840 | IMPDH Type 1 Enzyme Assay from Article 10.1021/jm070568j: \\Probing Binding Requirements of Type I and Type II Isoforms of Inosine Monophosphate Dehydrogenase with Adenine-Modified Nicotinamide Adenine Dinucleotide Analogues.\\ | 2007 | Journal of medicinal chemistry, Nov-15, Volume: 50, Issue:23
| Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |