Compounds > boronolide
Page last updated: 2024-11-12

boronolide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

boronolide: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10474298
CHEMBL ID514754
MeSH IDM0443792

Synonyms (6)

Synonym
CHEMBL514754
boronolide
33903-83-2
[(1r,2r,3s)-1,2-diacetyloxy-1-[(2r)-6-oxo-2,3-dihydropyran-2-yl]heptan-3-yl] acetate
(6r)-5,6-dihydro-6-[(1r,2r,3s)-1,2,3-tris(acetyloxy)heptyl]-2h-pyran-2-one
DTXSID601144712
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (13)

Assay IDTitleYearJournalArticle
AID338511Cytotoxicity against mouse P388 cells after 48 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338508Cytotoxicity against human Col1 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338497Antibacterial activity against Bacillus subtilis ATCC 6633 at < 100 ug/ml after 24 hrs at 37 degC by agar hole-plate diffusion assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338507Cytotoxicity against human SK-MEL-2 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338509Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338498Antibacterial activity against Staphylococcus aureus ATCC 6538 at < 100 ug/ml after 24 hrs at 37 degC by agar hole-plate diffusion assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338510Cytotoxicity against vinblastine-resistant human KBV1 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338506Cytotoxicity against human LUC1 cells after 48 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338504Cytotoxicity against human BC1 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338505Cytotoxicity against human HT1080 cells after 48 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338512Cytotoxicity against human A431 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338513Cytotoxicity against human LNCAP cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
AID338514Cytotoxicity against human ZR-75-1 cells after 72 hrs by sulforhodamine B assay1993Journal of natural products, Apr, Volume: 56, Issue:4
Structure and stereochemistry of pectinolides A-C, novel antimicrobial and cytotoxic 5,6-dihydro-alpha-pyrones from Hyptis pectinata.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.82 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.90 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
mannitol
[no description available]		2.0110mannitolallergen;
antiglaucoma drug;
compatible osmolytes;
Escherichia coli metabolite;
food anticaking agent;
food bulking agent;
food humectant;
food stabiliser;
food thickening agent;
hapten;
metabolite;
osmotic diuretic;
sweetening agent
erythrulose
[no description available]		2.0110ketotetrose;
primary alpha-hydroxy ketone;
secondary alpha-hydroxy ketone
nystatin a1
Nystatin: Macrolide antifungal antibiotic complex produced by Streptomyces noursei, S. aureus, and other Streptomyces species. The biologically active components of the complex are nystatin A1, A2, and A3.. nystatin : A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections.. nystatin A1 : A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.		1.9810nystatins
ConditionIndicatedRelationship StrengthStudiesTrials
Leukemia P388
An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.		01.9810