Compounds > bombinin h2
Page last updated: 2024-11-12

bombinin h2

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Description

bombinin H2: bombinin H4 differs from bombinin H2 in having a D-alloisoleucine residue; isolated from Bombina species [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID11851152
CHEMBL ID538628
MeSH IDM0497939

Synonyms (2)

Synonym
bombinin h2
CHEMBL538628
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (27)

Assay IDTitleYearJournalArticle
AID423118Antimicrobial activity against Stenotrophomonas maltophilia isolate 2 with AMK-CIP-CTX-IPM-MEM-SAM-TZP resistance phenotype assessed as assessed as time to kill at twofold bactericidal concentration2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422967Bactericidal activity against Acinetobacter baumannii isolate 1 with AMP-AMC-CFZ-CIP-IPM-LVX-PIP-SXT-TET resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422961Bactericidal activity against Staphylococcus aureus isolate 1 with AMC-AMP-CIP-ERY-GEN-OXA-RIF resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.5 hrs by2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423107Bactericidal activity against Enterococcus faecium isolate 3 with AMP-CIP-CTX-ERY-GEN-LVX-SXT-TEC-VAN resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in 20% heat-inactivated human serum after 1.5 2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423108Bactericidal activity against Staphylococcus aureus isolate 1 with AMC-AMP-CIP-ERY-GEN-OXA-RIF resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in 20% heat-inactivated human serum after 1.5 hrs by 2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422969Bactericidal activity against Acinetobacter baumannii isolate 3 with AMP-AMC-CFZ-CIP-IPM-SXT-TET-TOB resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.5 2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422965Bactericidal activity against Stenotrophomonas maltophilia isolate 2 with AMK-CIP-CTX-IPM-MEM-SAM-TZP resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.52008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422962Bactericidal activity against Staphylococcus aureus isolate 2 with AMC-AMP-CIP-ERY-GEN-LVX-OXA-RIF-TET resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423111Bactericidal activity against Pseudomonas aeruginosa isolate 1 with AMP-CFZ-CIP-CTX-CXM-GEN-LVX-SXT-TET resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in 20% heat-inactivated human serum after 1.2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423109Bactericidal activity against Stenotrophomonas maltophilia isolate 2 with AMK-CIP-CTX-IPM-MEM-SAM-TZP resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in 20% heat-inactivated human serum after 1.5 2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423124Antimicrobial activity against Enterococcus faecium isolate 3 with AMP-CIP-CTX-ERY-GEN-LVX-SXT-TEC-VAN resistance phenotype assessed as time to kill at twofold the bactericidal concentration2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423105Bactericidal activity against Pseudomonas aeruginosa isolate 2 with AMP-CFZ-CIP-CTX-CXM-GEN-LVX-IPM-MEM-SXT-TET resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.42008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422964Bactericidal activity against Stenotrophomonas maltophilia isolate 1 with AMK-CIP-CTX-IPM-MEM-SAM-TZP resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.52008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422958Bactericidal activity against Enterococcus faecium isolate 3 with AMP-CIP-CTX-ERY-GEN-LVX-SXT-TEC-VAN resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.52008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423123Antimicrobial activity against Enterococcus faecium isolate 3 with AMP-CIP-CTX-ERY-GEN-LVX-SXT-TEC-VAN resistance phenotype assessed as time to kill at bactericidal concentration2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423106Bactericidal activity against Pseudomonas aeruginosa isolate 3 with AMP-CFZ-CTX-CIP-GEN-IPM-LVX-SXT-TET-TOB resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 aft2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422959Bactericidal activity against Enterococcus faecium isolate 5 with AMP-AMC-CIP-CLI-ERY-GEN-KAN-LVX-SXT-TEC-VAN resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 a2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423120Antimicrobial activity against Pseudomonas aeruginosa isolate 1 with AMP-CFZ-CIP-CTX-CXM-GEN-LVX-SXT-TET resistance phenotype at bactericidal concentration after 30 mins by time kill assay2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423121Antimicrobial activity against Pseudomonas aeruginosa isolate 1 with AMP-CFZ-CIP-CTX-CXM-GEN-LVX-SXT-TET resistance phenotype at twofold bactericidal concentration after 10 to 30 mins by time kill assay2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422966Bactericidal activity against Stenotrophomonas maltophilia isolate 4 with AMK-CAZ-CIP-FEP-IPM-SAM-TZP resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.52008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423119Antimicrobial activity against Acinetobacter baumannii isolate 3 with AMP-AMC-CFZ-CIP-IPM-SXT-TET-TOB resistance phenotype assessed as time to kill at bactericidal concentration2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422968Bactericidal activity against Acinetobacter baumannii isolate 2 with AMP-CFZ-CIP-LVX-PIP-SXT resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.5 hrs by l2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422963Bactericidal activity against Staphylococcus aureus isolate 3 with AMC-AMP-CIP-ERY-GEN-LVX-OXA resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 1.5 hrs by2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423117Antimicrobial activity against Staphylococcus aureus isolate 1 with AMC-AMP-CIP-ERY-GEN-OXA-RIF resistance phenotype at twofold the bactericidal concentration within 30 mins2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422970Bactericidal activity against Pseudomonas aeruginosa isolate 1 with AMP-CFZ-CIP-CTX-CXM-GEN-LVX-SXT-TET resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 7.4 after 12008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID422960Bactericidal activity against Enterococcus faecium isolate 6 with AMP-AMC-CLI-CRO-CTX-CIP-ERY-GEN-KAN-LVX-SXT-VAN resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in sodium phosphate buffer at pH 72008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
AID423110Bactericidal activity against Acinetobacter baumannii isolate 3 with AMP-AMC-CFZ-CIP-IPM-SXT-TET-TOB resistance phenotype assessed as concentration required for >= 3 log10 CFU/ml reduction in viable bacteria in 20% heat-inactivated human serum after 1.5 h2008Antimicrobial agents and chemotherapy, Jan, Volume: 52, Issue:1
Comparative analysis of the bactericidal activities of amphibian peptide analogues against multidrug-resistant nosocomial bacterial strains.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's6 (50.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.94

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.94 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.51 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.94)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (16.67%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (83.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
glycine
[no description available]		7.0410alpha-amino acid;
amino acid zwitterion;
proteinogenic amino acid;
serine family amino acid		EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor;
fundamental metabolite;
hepatoprotective agent;
micronutrient;
neurotransmitter;
NMDA receptor agonist;
nutraceutical
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.		2.0610amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
isoleucine
Isoleucine: An essential branched-chain aliphatic amino acid found in many proteins. It is an isomer of LEUCINE. It is important in hemoglobin synthesis and regulation of blood sugar and energy levels.. isoleucine : A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration.. L-isoleucine : The L-enantiomer of isoleucine.		2.5120aspartate family amino acid;
isoleucine;
L-alpha-amino acid zwitterion;
L-alpha-amino acid;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		2.1310dihydrogen
temporin
temporin: isolated from frogs Rana temporaria & R. clamitans; has many isoforms; amino acid sequence in first source		3.5420
ConditionIndicatedRelationship StrengthStudiesTrials
Health Care Associated Infection
[description not available]		02.0410
Cross Infection
Any infection which a patient contracts in a health-care institution.		02.0410
Bacterial Disease
[description not available]		02.1510
Candida Infection
[description not available]		02.1510
Extravascular Hemolysis
[description not available]		02.1510
Bacterial Infections
Infections by bacteria, general or unspecified.		02.1510
Candidiasis
Infection with a fungus of the genus CANDIDA. It is usually a superficial infection of the moist areas of the body and is generally caused by CANDIDA ALBICANS. (Dorland, 27th ed)		02.1510
Hemolysis
The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.		02.1510