| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1345886 | Human sphingosine kinase 1 (Sphingosine kinase) | 2008 | Blood, Aug-15, Volume: 112, Issue:4
| A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia. |
| AID1501052 | Inhibition of V5-His-tagged human SphK1 using sphingosine as substrate in presence of [gamma-32P]ATP | 2017 | European journal of medicinal chemistry, Oct-20, Volume: 139 | An integrative study to identify novel scaffolds for sphingosine kinase 1 inhibitors. |
| AID745112 | Inhibition of human V5-His-tagged SK1 expressed in HEK293 cells using sphingosine as substrate at 50 uM FRET assay relative to control | 2013 | Bioorganic & medicinal chemistry, May-01, Volume: 21, Issue:9
| Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators. |
| AID1199975 | Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liquid scintillation counting | 2015 | Journal of medicinal chemistry, Feb-26, Volume: 58, Issue:4
| Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors. |
| AID1151447 | Competitive inhibition of V5-His-tagged human SphK2 expressed in HEK293 cells assessed as S1P production using sphingosine and [gamma-32P]ATP as substrate by thin layer chromatography | 2014 | Journal of medicinal chemistry, Jul-10, Volume: 57, Issue:13
| Importance of sphingosine kinase (SphK) as a target in developing cancer therapeutics and recent developments in the synthesis of novel SphK inhibitors. |
| AID1199976 | Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liquid scintillation counting | 2015 | Journal of medicinal chemistry, Feb-26, Volume: 58, Issue:4
| Structure-activity relationship studies and in vivo activity of guanidine-based sphingosine kinase inhibitors: discovery of SphK1- and SphK2-selective inhibitors. |
| AID1055358 | Inhibition of recombinant sphingosine kinase 1 (unknown origin) expressed in HEK293 cells using sphingosine as substrate at 50 uM after 30 mins relative to control in presence of [gamma32P]-ATP | 2013 | Journal of medicinal chemistry, Nov-27, Volume: 56, Issue:22
| Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors. |
| AID1055359 | Inhibition of sphingosine kinase 1 (unknown origin) | 2013 | Journal of medicinal chemistry, Nov-27, Volume: 56, Issue:22
| Structure-activity relationships and molecular modeling of sphingosine kinase inhibitors. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |