Page last updated: 2024-12-08

bis(1,2-bis(diphenylphosphino)ethane)gold(i)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

bis(1,2-bis(diphenylphosphino)ethane)gold(I): RN given for parent cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID162561
MeSH IDM0143444

Synonyms (5)

Synonym
47895-18-1
(au(dppe)2)cl
gold(1+), bis(1,2-ethanediylbis(diphenylphosphine)-p,p')-, (t-4)-
bis(1,2-bis(diphenylphosphino)ethane)gold(i)
2-diphenylphosphanylethyl(diphenyl)phosphane;gold(1+)

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" In initial experiments we characterized some pharmacokinetic aspects of the disposition of these amines."( Disposition of radioiodinated benzylguanidines in perfused rabbit lung: pharmacokinetics and effect of an organo-gold complexed antineoplastic agent.
Gillis, CN; Lazo, JS; Pitt, BR; Weng, WL, 1990
)
0.28

Dosage Studied

ExcerptRelevanceReference
" This compound was also the most active of those tested in vivo, giving a growth delay of 9 days following daily intraperitoneal dosing (10 days) at 4 micromol kg(-1) day(-1)."( Role of lipophilicity in determining cellular uptake and antitumour activity of gold phosphine complexes.
Baguley, BC; Berners-Price, SJ; Bowen, RJ; Brouwer, W; Ding, L; Galettis, P; McKeage, MJ; Zhuang, L, 2000
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (11)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (54.55)18.7374
1990's4 (36.36)18.2507
2000's1 (9.09)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.93

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.93 (24.57)
Research Supply Index2.48 (2.92)
Research Growth Index4.42 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.93)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other11 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]