bicyclo(2.2.2)oct-2-ene profile

Bicyclo(2.2.2)oct-2-ene is a strained bicyclic alkene. It is known for its interesting reactivity and potential applications in organic synthesis. The compound can be synthesized through various methods, including the Diels-Alder reaction and the ring-closing metathesis of cyclohexene derivatives. The strained nature of the bicyclic system makes it susceptible to ring-opening reactions. Its reactivity has been explored in various studies, including its use as a dienophile in Diels-Alder reactions, a substrate for oxidation reactions, and a precursor to other complex molecules. The compound has also been studied for its potential applications in the development of new materials and pharmaceuticals. Bicyclo(2.2.2)oct-2-ene is a useful synthetic building block and a model system for understanding the chemistry of strained systems.'

bicyclo(2.2.2)oct-2-ene: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	13608
MeSH ID	M0421262

Synonyms (16)

Synonym
BB 0262307
bicyclo[2.2.2]octene
inchi=1/c8h12/c1-2-8-5-3-7(1)4-6-8/h1-2,7-8h,3-6h
bicyclo[2.2.2]oct-2-ene
FT-0693091
AKOS006273027
bicyclo(2.2.2)oct-2-ene
931-64-6
2,2,2-bicyclooctene-2
bicyclo[2,2,2]-2-octene
bicyclo[2.2.2]-2-octene
3,6-endoethylenecyclohexene
cyclohexene, 3,6-endo-(1,2-ethanediyl)-
2,2,2-bicyclo-2-octene
DTXSID40239271
(1s,4s)-bicyclo[2.2.2]oct-2-ene

Research

Studies (8)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (50.00)	29.6817
2010's	4 (50.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	21.50 (24.57)
Research Supply Index	2.20 (2.92)
Research Growth Index	4.40 (4.65)
Search Engine Demand Index	18.60 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (21.50)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	8 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
1-anilino-8-naphthalenesulfonate 1-anilino-8-naphthalenesulfonate: RN given refers to parent cpd. 8-anilinonaphthalene-1-sulfonic acid : A naphthalenesulfonic acid that is naphthalene-1-sulfonic acid substituted by a phenylamino group at position 8.	2.05	1	aminonaphthalene; naphthalenesulfonic acid	fluorescent probe
1,4-cyclohexadiene [no description available]	2.01	1	cyclohexadiene
rhodium Rhodium: A hard and rare metal of the platinum group, atomic number 45, atomic weight 102.905, symbol Rh.. rhodium atom : A cobalt group element atom of atomic number 45.	2.05	1	cobalt group element atom
alkenes [no description available]	2.01	1
lignans Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)	2.1	1
caffeic acid trans-caffeic acid : The trans-isomer of caffeic acid.	2.1	1	caffeic acid	geroprotector; mouse metabolite

bicyclo(2.2.2)oct-2-ene

Description