bgugaine: a pyrrolidine alkaloid from tuber, Arisarum vulgare that is a strong hepatoxin in liver cell cultures [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Arisarum | genus | [no description available] | Araceae | A plant family of the order ALISMATALES. Many members contain OXALIC ACID and calcium oxalate (OXALATES).[MeSH] |
| Arisarum vulgare | species | [no description available] | Araceae | A plant family of the order ALISMATALES. Many members contain OXALIC ACID and calcium oxalate (OXALATES).[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 461557 |
| MeSH ID | M0302806 |
| Synonym |
|---|
| bgugaine |
| pyrrolidine, 1-methyl-2-tetradecyl-, (2r)- |
| (2r)-1-methyl-2-tetradecyl-pyrrolidine |
| (2r)-1-methyl-2-tetradecylpyrrolidine |
Bgugaine is a natural pyrrolidine alkaloid from Arisarum vulgare. It shows antifungal and antibacterial activity.
| Excerpt | Reference | Relevance |
|---|---|---|
| "(R)-Bgugaine is a natural pyrrolidine alkaloid from Arisarum vulgare, which shows antifungal and antibacterial activity. " | ( Synthesis of (R)-norbgugaine and its potential as quorum sensing inhibitor against Pseudomonas aeruginosa. Bhat, C; D'Souza, L; Majik, MS; Naik, D; Tilve, S; Tilvi, S, 2013) | 1.27 |
| Excerpt | Reference | Relevance |
|---|---|---|
| " This alkaloid is an isomer of R-bgugaine [2], an alkaloid isolated from Arisarum vulgare, an Araceae toxic plant of Morocco." | ( Cytotoxic effect and electrophysiological activity of (S)-bgugaine, an alkylpyrrolidine alkaloid against MRC-5 fibroblasts. Buclon, M; Fontange, R; Lamkadem, M; Melhaoui, A; Mimouni, J, 2000) | 0.83 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||