Beta-hydroxyphenylpropionic acid (BHPA) is a naturally occurring organic compound found in various plants. It is a derivative of phenylpropionic acid and is known for its antioxidant and anti-inflammatory properties. BHPA is studied for its potential therapeutic applications in treating conditions like diabetes, obesity, and cardiovascular disease. It is believed to exert its effects by modulating the activity of enzymes and signaling pathways involved in metabolism and inflammation. Several studies have explored the synthesis of BHPA through various methods, including enzymatic catalysis and microbial fermentation. The compound has also been investigated as a potential precursor for the synthesis of other bioactive compounds.'
beta-hydroxyphenylpropionic acid: benzoic acid metabolite in urine [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
3-hydroxy-3-phenylpropionic acid : A 3-hydroxy carboxylic acid that is 3-phenylpropionic acid in which one of the hydrogens beta to the carboxy group is replaced by a hydroxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 92959 |
| CHEBI ID | 19929 |
| SCHEMBL ID | 186610 |
| MeSH ID | M0099106 |
| Synonym |
|---|
| nsc120422 |
| 3480-87-3 |
| nsc-120422 |
| nsc16256 |
| nsc-16256 |
| OPREA1_612432 , |
| 3-hydroxy-3-phenylpropanoic acid |
| CHEBI:19929 |
| 3-hydroxy-3-phenylpropionic acid |
| beta-hydroxyphenylpropionic acid |
| FT-0652077 |
| 3-hydroxy-3-phenyl-propionic acid |
| A822414 |
| 3-hydroxy-3-phenyl-propanoic acid |
| benzenepropanoic acid, beta-hydroxy- |
| s2w4lws09c , |
| nsc 16256 |
| unii-s2w4lws09c |
| nsc 120422 |
| FT-0605218 |
| FT-0605100 |
| AKOS009158709 |
| FD1325 |
| H1394 |
| SCHEMBL186610 |
| carbonicacidethylesterm-tolylester |
| propanoic acid, 3-hydroxy-3-phenyl |
| 3-hydroxy-3-phenylpropanoic acid # |
| hydroxybenzenepropanoic acid, beta |
| .beta.-hydroxyphenylpropionic acid |
| AC-23820 |
| mfcd00137907 |
| GS-4068 |
| J-019766 |
| CS-W021936 |
| SY017555 |
| Q27109264 |
| 3-hydroxy-3-phenylpropanoicacid |
| EN300-111801 |
| DTXSID70901075 |
| noname_130 |
| (r)-(+)-3-hydroxy-3-phenylpropionicacid |
| CAA76842 |
| Z982132010 |
| Class | Description |
|---|---|
| monocarboxylic acid | An oxoacid containing a single carboxy group. |
| 3-hydroxy carboxylic acid | Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.04) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||