| Assay ID | Title | Year | Journal | Article |
|---|
| AID615261 | Cytotoxicity against human HeLa cells by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9
| Synthesis and antitumour activity of β-hydroxyisovalerylshikonin analogues. |
| AID644401 | Inhibition of alpha-glucosidase at 200 uM | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID305640 | Inhibition of human ACAT2 expressed in Hi5 cells | 2007 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 17, Issue:4
| Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon. |
| AID644394 | Competitive inhibition of Clostridium perfringens ATCC 10543 sialidase Nan1 c-terminal catalytic domain using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate by Lineweaver-Burk and Dixon plot analysis | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID669244 | Cytotoxicity against human HCT116 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID669243 | Cytotoxicity against human U251 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID669247 | Cytotoxicity against human WM9 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID644402 | Inhibition of beta-glucosidase at 200 uM | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID669249 | Cytotoxicity against human MRC5 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID644395 | Inhibition of recombinant influenza A virus H1N1 A/Bervig_Mission/1/18 sialidase activity using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate by fluorimetric analysis | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID363329 | Cytotoxicity against MDR1 Pgp overexpressing human HepG2 cells after 24 hrs by MTT assay | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. |
| AID669245 | Cytotoxicity against human SBcl2 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID644397 | Inhibition of Clostridium perfringens ATCC 10543 sialidase Nan1 c-terminal catalytic domain using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate at IC50 concentration pre-incubated for 10 mins prior substrate additio | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID669250 | Selectivity ratio of IC50 for human MRC5 cells to IC50 for human CCRF-CEM cells | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID644393 | Inhibition of Clostridium perfringens ATCC 10543 sialidase Nan1 c-terminal catalytic domain using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate by fluorimetric analysis | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID669242 | Cytotoxicity against human MDA-MB-231 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID644398 | Reversible inhibition of Clostridium perfringens ATCC 10543 sialidase Nan1 c-terminal catalytic domain using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate compound pre-incubated prior to substrate addition by fluori | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID669246 | Cytotoxicity against human WM35 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID669241 | Cytotoxicity against human CCRF-CEM cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| AID363328 | Cytotoxicity against MDR1 Pgp under-expressing human HCT116 cells after 24 hrs by MTT assay | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. |
| AID305641 | Inhibition of human ACAT1 expressed in Hi5 cells | 2007 | Bioorganic & medicinal chemistry letters, Feb-15, Volume: 17, Issue:4
| Human ACAT inhibitory effects of shikonin derivatives from Lithospermum erythrorhizon. |
| AID644403 | Inhibition of rhamnosidase at 200 uM | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID644396 | Noncompetitive inhibition of recombinant influenza A virus H1N1 A/Bervig_Mission/1/18 sialidase activity using 4-methylumbelliferyl-alpha-D-N-acetylneuraminic acid sodium salt hydrate as substrate by Lineweaver-Burk and Dixon plot analysis | 2012 | Bioorganic & medicinal chemistry, Mar-01, Volume: 20, Issue:5
| Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. |
| AID615262 | Cytotoxicity against human DU145 cells by MTT assay | 2011 | European journal of medicinal chemistry, Sep, Volume: 46, Issue:9
| Synthesis and antitumour activity of β-hydroxyisovalerylshikonin analogues. |
| AID669248 | Cytotoxicity against human WM164 cells after 72 hrs by XTT assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5
| Naphthoquinones from Onosma paniculata induce cell-cycle arrest and apoptosis in melanoma Cells. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |