Page last updated: 2024-11-13
berkeleyacetal c
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
berkeleyacetal C: from a deep water acid mine waste Penicillium; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 24179736 |
| CHEMBL ID | 400716 |
| MeSH ID | M0517182 |
Synonyms (5)
| Synonym |
|---|
| berkeleyacetal c |
| CHEMBL400716 |
| HY-N10175 |
| CS-0370061 |
| (1r,2s,11r,12r,14r,17r,19s,21s)-2,6,6,14,19-pentamethylspiro[7,16,18-trioxapentacyclo[12.6.1.02,12.05,10.017,21]henicosa-4,9-diene-11,2'-oxirane]-3,8,15,20-tetrone |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1315278 | Cytotoxicity against LPS-stimulated human BV2 cells assessed as decrease in cell viability up to 100 uM preincubated for 10 mins followed by LPS stimulation for 24 hrs by MTT assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Nitric Oxide Inhibitory Meroterpenoids from the Fungus Penicillium purpurogenum MHZ 111. |
| AID311774 | Growth inhibition of human NCI-H460 cells | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | The berkeleyacetals, three meroterpenes from a deep water acid mine waste Penicillium. |
| AID1315276 | Antineuroinflammatory activity in human BV2 cells assessed as inhibition of LPS-induced nitric oxide production preincubated for 10 mins followed by LPS stimulation for 24 hrs by Griess assay | 2016 | Journal of natural products, 05-27, Volume: 79, Issue:5 | Nitric Oxide Inhibitory Meroterpenoids from the Fungus Penicillium purpurogenum MHZ 111. |
| AID311773 | Inhibition of caspase 1 | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | The berkeleyacetals, three meroterpenes from a deep water acid mine waste Penicillium. |
| AID311772 | Inhibition of MMP3 | 2007 | Journal of natural products, Nov, Volume: 70, Issue:11 | The berkeleyacetals, three meroterpenes from a deep water acid mine waste Penicillium. |
| AID1502661 | Cytotoxicity against mouse RAW264.7 cells by MTT assay | 2017 | Journal of natural products, 10-27, Volume: 80, Issue:10 | 3,5-Dimethylorsellinic Acid Derived Meroterpenoids from Penicillium chrysogenum MT-12, an Endophytic Fungus Isolated from Huperzia serrata. |
| AID1502659 | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells after 24 hrs by Griess assay | 2017 | Journal of natural products, 10-27, Volume: 80, Issue:10 | 3,5-Dimethylorsellinic Acid Derived Meroterpenoids from Penicillium chrysogenum MT-12, an Endophytic Fungus Isolated from Huperzia serrata. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.28
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.28) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||