Benzoyl glucuronide is a metabolite of benzoyl chloride, a common industrial chemical and a component of some pesticides. It is formed in the liver by the enzyme UDP-glucuronosyltransferase. Benzoyl glucuronide is excreted in the urine and is generally considered to be a detoxification product. Studies on benzoyl glucuronide are primarily focused on understanding its role in the metabolism and excretion of benzoyl chloride and other related compounds. Research has shown that benzoyl glucuronide can undergo further metabolism in the gut, leading to the formation of benzoyl-CoA, a compound that can contribute to liver toxicity. The study of benzoyl glucuronide is important for assessing the safety of exposure to benzoyl chloride and other related compounds, as well as for understanding the role of glucuronidation in drug metabolism.'
benzoyl glucuronide: RN given refers to (beta-D)-isomer [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 115145 |
| CHEBI ID | 168513 |
| MeSH ID | M0113688 |
| Synonym |
|---|
| CHEBI:168513 |
| 19237-53-7 |
| benzoyl glucuronide (benzoic acid) |
| (2s,3s,4s,5r,6s)-6-benzoyloxy-3,4,5-trihydroxyoxane-2-carboxylic acid |
| benzoyl glucuronide |
| beta-d-glucopyranuronic acid, 1-benzoate |
| oc94t61o9a , |
| unii-oc94t61o9a |
| .beta.-d-glucopyranuronic acid, 1-benzoate |
| glucopyranuronic acid, 1-benzoate, .beta.-d- |
| benzoyl-.beta.-d-glucuronide |
| benzoic acid .beta.-d-glucuronide |
| benzoic acid glucuronide |
| (2s,3s,4s,5r,6s)-6-(benzoyloxy)-3,4,5-trihydroxyoxane-2-carboxylic acid |
| benzoic acid acyl-beta-d-glucuronide |
| DTXSID90940901 |
| 1-o-benzoylhexopyranuronic acid |
| Q27285571 |
| Class | Description |
|---|---|
| glucosiduronic acid | Any substance produced by linking glucuronic acid to another substance via a glycosidic bond. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (20.23) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||