be 14106 profile

BE 14106: structure given in first source; isolated from Streptomyces; inhibits growth of vincristine-resistant murine leukemia cells [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	6439426
MeSH ID	M0204743

Synonyms (7)

Synonym
gt32-a
140212-86-8
be 14106
azacycloeicosa-3,5,7,11,13,15,17-heptaen-2-one, 9,10-dihydroxy-7,15-dimethyl-20-(2-hexenyl)-
9,10-dihydroxy-7,15-dimethyl-20-(2-hexenyl)azacycloeicosa-3,5,7,11,13,15,17-heptaen-2-one
azacycloeicosa-3,5,7,11,13,15,17-heptaen-2-one, 20-(2-hexenyl)-9,10-dihydroxy-7,15-dimethyl-
(3z,5z,7z,11z,13z,15z,17z)-20-[(e)-hex-2-enyl]-9,10-dihydroxy-7,15-dimethyl-1-azacycloicosa-3,5,7,11,13,15,17-heptaen-2-one

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	2 (40.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.58

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.58 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.37 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.58)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
histidine Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.	2	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite
alkenes [no description available]	2.02	1
vicenistatin vicenistatin: a macrocyclic lactam from Streptomyces sp. HC34; structure given in first source	2.02	1	azamacrocycle; lactam
heronamide c heronamide C: elicits changes in cell morphology of cancer cells; isolated from Streptomyces; structure in first source	2.13	1
stubomycin stubomycin: contains polyene amide group; from Streptomyces	2.02	1

Condition	Indicated	Relationship Strength	Studies	Trials
Cancer of Pancreas [description not available]	0	2	1	0
Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).	0	2	1	0

be 14106

Description