Substance | Relationship Strength | Studies | Trials | Classes | Roles |
etidronate Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.. etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces. | 2.88 | 4 | 0 | 1,1-bis(phosphonic acid) | antineoplastic agent; bone density conservation agent; chelator |
pamidronate [no description available] | 2.37 | 2 | 0 | phosphonoacetic acid | |
adenosine diphosphate Adenosine Diphosphate: Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. | 2 | 1 | 0 | adenosine 5'-phosphate; purine ribonucleoside 5'-diphosphate | fundamental metabolite; human metabolite |
3,4-dihydroxyacetophenone 3,4-dihydroxyacetophenone: shortens action potential duration of cardiac cells. 3',4'-dihydroxyacetophenone : A dihydroxyacetophenone that is acetophenone carrying hydroxy groups at positions 3' and 4'. | 2.25 | 1 | 0 | acetophenones; catechols; dihydroxyacetophenone | metabolite |
lanthanum [no description available] | 2.36 | 2 | 0 | f-block element atom; lanthanoid atom; scandium group element atom | |
clodronic acid Clodronic Acid: A diphosphonate which affects calcium metabolism. It inhibits bone resorption and soft tissue calcification.. clodronic acid : An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. | 1.97 | 1 | 0 | 1,1-bis(phosphonic acid); one-carbon compound; organochlorine compound | antineoplastic agent; bone density conservation agent |
adenylyl imidodiphosphate Adenylyl Imidodiphosphate: 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid. An analog of ATP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It is a potent competitive inhibitor of soluble and membrane-bound mitochondrial ATPase and also inhibits ATP-dependent reactions of oxidative phosphorylation. | 2 | 1 | 0 | adenosine 5'-phosphate | |
azides Azides: Organic or inorganic compounds that contain the -N3 group.. azide : Any nitrogen molecular entity containing the group -N3. | 2 | 1 | 0 | pseudohalide anion | mitochondrial respiratory-chain inhibitor |
trimazosin trimazosin: RN given refers to parent cpd; structure | 1.96 | 1 | 0 | N-arylpiperazine | |
elastin [no description available] | 1.96 | 1 | 0 | oligopeptide | |
cysteine Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. | 2.43 | 2 | 0 | cysteinium | fundamental metabolite |