| Assay ID | Title | Year | Journal | Article |
|---|
| AID1631896 | Inhibition of cell invasion in human H1299 cells at 1 to 3 uM after 24 hrs by Boyden's chamber transwell invasion assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379315 | Antimicrobial activity against Hansenula anomala HUT 7083 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631897 | Inhibition of MMP9 activity in human H1299 cells at 3 uM after 48 hrs by gelatin zymography | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631894 | Inhibition of beta-catenin signalling in human A549 cells assessed as reduction in beta-catenin level at 3 to 9 uM after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379316 | Antimicrobial activity against Candida albicans TIMM 0134 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631877 | Cytotoxicity against human A549 cells assessed as cell survival up to 10 uM incubated for 24 hrs by CCK8 assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631879 | Induction of apoptosis in human A549 cells assessed as dead cells at 9 uM after 24 hrs by flow cytometry (Rvb = 0%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631884 | Inhibition of cell invasion in human A549 cells at 1 to 3 uM after 24 hrs by Boyden's chamber transwell invasion assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631885 | Inhibition of MMP2 activity in human A549 cells at 3 to 9 uM after 48 hrs by gelatin zymography | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631878 | Induction of apoptosis in human A549 cells assessed as live cells at 9 uM after 24 hrs by flow cytometry (Rvb = 76.65%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379318 | Antimicrobial activity against Kloeckera apiculata IFO 154 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631900 | Inhibition of MMP2 mRNA expression in human H1299 cells at 3 uM after 48 hrs by RT-PCR analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631895 | Antimigratory activity in human H1299 cells at 1 to 6 uM incubated for 24 hrs by wound healing assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631887 | Inhibition of MMP2 mRNA expression in human A549 cells at 3 uM after 48 hrs by RT-PCR analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631890 | Inhibition of p38 phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631881 | Cell cycle arrest in human A549 cells assessed as accumulation at S phase at 9 uM after 24 hrs by flow cytometry (Rvb = 18.3%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631876 | Induction of apoptosis in human A549 cells assessed as late apoptotic cells at 9 uM after 24 hrs by flow cytometry (Rvb = 7.9%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379317 | Antimicrobial activity against Pichia nakazawae HUT 1688 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631875 | Induction of apoptosis in human A549 cells assessed as early apoptotic cells at 9 uM after 24 hrs by flow cytometry (Rvb = 15.45%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379319 | Antimicrobial activity against Debaryomyces hansenii IFO 18 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631898 | Inhibition of MMP2 activity in human H1299 cells at 3 uM after 48 hrs by gelatin zymography | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631883 | Antimigratory activity in human A549 cells incubated for 24 hrs by wound healing assay | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631882 | Cell cycle arrest in human A549 cells assessed as accumulation at G2/M phase at 9 uM after 24 hrs by flow cytometry (Rvb = 15.1%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631892 | Inhibition of c-Src phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID379314 | Antimicrobial activity against Saccharomyces cerevisiae IFO 203 after 48 hrs by agar dilution method | 2000 | Journal of natural products, Mar, Volume: 63, Issue:3
| Antiyeast steroidal saponins from Yucca schidigera (Mohave yucca), a new anti-food-deteriorating agent. |
| AID1631899 | Inhibition of MMP9 mRNA expression in human H1299 cells at 3 uM after 48 hrs by RT-PCR analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631880 | Cell cycle arrest in human A549 cells assessed as accumulation at G0/G1 phase at 9 uM after 24 hrs by flow cytometry (Rvb = 66.5%) | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631893 | Inhibition of FAK phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631886 | Inhibition of MMP9 activity in human A549 cells at 3 to 9 uM after 48 hrs by gelatin zymography | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631889 | Inhibition of ERK1/2 phosphorylation in human A549 cells after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631888 | Inhibition of MMP9 mRNA expression in human A549 cells at 3 uM after 48 hrs by RT-PCR analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| AID1631891 | Inhibition of JNK phosphorylation in human A549 cells at 3 to 9 uM after 24 hrs by Western blot analysis | 2016 | Bioorganic & medicinal chemistry letters, 08-15, Volume: 26, Issue:16
| Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and β-catenin signaling pathways. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |