arginyl-threonyl-prolyl-prolyl-prolyl-seryl-glycine profile

arginyl-threonyl-prolyl-prolyl-prolyl-seryl-glycine: synthetic heptapeptide substrates for protein kinase; SP-7 is D-Arg [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID Source	ID
PubMed CID	146985
MeSH ID	M0138124

Synonyms (9)

Synonym
sp 6
2-[[(2s)-2-[[(2s)-1-[(2s)-1-[(2s)-1-[(2s,3r)-2-[[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]acetic acid
n-(n-(1-(1-(1-(n-l-arginyl-l-threonyl)-l-prolyl)-l-prolyl)-l-prolyl)-l-seryl)glycine
arginyl-threonyl-prolyl-prolyl-prolyl-seryl-glycine
101020-48-8
sp 7
arg-thr-pro-pro-pro-ser-gly
glycine, n-(n-(1-(1-(1-(n-l-arginyl-l-threonyl)-l-prolyl)-l-prolyl)-l-prolyl)-l-seryl)-
DTXSID50143678

Research Excerpts

Dosage Studied

Excerpt	Relevance	Reference
" Intravenous injection of SP-6 in rabbits at the dosage of 14."	( [Synthesis and biological activity of an analogue of active fragment (SP-6) of substance P]. Hu, XY; Li, RD; Wang, ZY; Yang, GL, 1994)	0.29

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	1 (14.29)	18.7374
1990's	1 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	5 (71.43)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.92

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	11.92 (24.57)
Research Supply Index	2.40 (2.92)
Research Growth Index	4.32 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (11.92)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	3 (42.86%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	4 (57.14%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Trials	Classes	Roles
threonine Threonine: An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins.. threonine : An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group.	1.96	1	0	amino acid zwitterion; aspartate family amino acid; L-alpha-amino acid; proteinogenic amino acid; threonine	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; plant metabolite; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies	Trials
Menstruation, Painful [description not available]	4.54	2	2
Dysmenorrhea Painful menstruation.	4.54	2	2
Colicky Pain [description not available]	3.56	1	1
Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	3.56	1	1
Abdominal Pain Sensation of discomfort, distress, or agony in the abdominal region.	3.56	1	1
Breast Cancer [description not available]	2.1	1	0
Breast Neoplasms Tumors or cancer of the human BREAST.	2.1	1	0
Muscle Contraction A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.	1.98	1	0

arginyl-threonyl-prolyl-prolyl-prolyl-seryl-glycine

Description