Compounds > ardisicrenoside a
Page last updated: 2024-11-12

ardisicrenoside a

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ardisicrenoside A: isolated from Ardisia crenata; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10260582
CHEMBL ID373378
MeSH IDM0242833

Synonyms (7)

Synonym
CHEMBL373378
ardisicrenoside a
160824-52-2
CS-0140296
HY-N8199
AKOS040761370
FS-7255
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID277218Cytotoxicity against human KATO3 cell line by MTT assay2007Journal of natural products, Feb, Volume: 70, Issue:2
Biologically active triterpenoid saponins from Ardisia japonica.
AID277217Cytotoxicity against human HL60 cell line by MTT assay2007Journal of natural products, Feb, Volume: 70, Issue:2
Biologically active triterpenoid saponins from Ardisia japonica.
AID277219Cytotoxicity against human A549 cell line by MTT assay2007Journal of natural products, Feb, Volume: 70, Issue:2
Biologically active triterpenoid saponins from Ardisia japonica.
AID683330Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells.
AID683331Cytotoxicity against human HL-7702 cells after 72 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells.
AID683329Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay2012Bioorganic & medicinal chemistry letters, Oct-01, Volume: 22, Issue:19
13,28-Epoxy triterpenoid saponins from Ardisia japonica selectively inhibit proliferation of liver cancer cells without affecting normal liver cells.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.87

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.87 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.66 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.87)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
oleanolic acid
[no description available]		3.830hydroxy monocarboxylic acid;
pentacyclic triterpenoid		plant metabolite
etoposide
[no description available]		2.0310beta-D-glucoside;
furonaphthodioxole;
organic heterotetracyclic compound		antineoplastic agent;
DNA synthesis inhibitor
epirubicin
Epirubicin: An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.		2.0710aminoglycoside;
anthracycline antibiotic;
anthracycline;
deoxy hexoside;
monosaccharide derivative;
p-quinones;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		antimicrobial agent;
antineoplastic agent;
EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor
ardisiacrispin a
ardisiacrispin A: utero-contracting oleanane triterpene saponin from Ardisia crispa		1.9810
cyclamin
cyclamin: antineoplastic from Ardisia japonica; structure in first source		2.4620triterpenoid
beta-escin
[no description available]		3.830
glutinol
glutinol: from a medicinal lichen, Usnea longissima; structure in first source. glutinol : A pentacyclic triterpenoid that is picene which has been fully hydrogenated except for a double bond between the 4a and 5 positions and is substituted by methyl groups at the 4, 4, 6bbeta, 8abeta, 11, 11, 12balpha and 14bbeta positions, and by a hydroxy group at the 3beta position.		2.0310pentacyclic triterpenoid;
secondary alcohol
ardisiacrispin b
ardisiacrispin B: untero-contracting oleanane triterpene saponin form Ardisia crispa; structure given in first source		2.9440
ConditionIndicatedRelationship StrengthStudiesTrials
Cancer of Liver
[description not available]		02.0710
Liver Neoplasms
Tumors or cancer of the LIVER.		02.0710