Page last updated: 2024-12-08

arabinonate-5-phosphate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

arabinonate-5-phosphate: competitive inhibitor of glucosephosphate isomerase [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID191445
SCHEMBL ID4330442
MeSH IDM0059079

Synonyms (16)

Synonym
5-o-phosphono-d-arabinonic acid
5-phosphoarabinonic acid
PA5 ,
DB03042
1G98
1GZV
57287-61-3
SCHEMBL4330442
(2s,3r,4r)-2,3,4-trihydroxy-5-phosphonooxypentanoic acid
d-arabinonic acid, 5-(dihydrogen phosphate)
5-phosphoarabinonate
arabinonate-5-phosphate
14405-05-1
DTXSID70972801
5-o-phosphonopentonic acid
PD059872
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (2)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, Phosphoglucose IsomeraseOryctolagus cuniculus (rabbit)Ki2.00002.00002.00002.0000AID977610
Chain B, Phosphoglucose IsomeraseOryctolagus cuniculus (rabbit)Ki2.00002.00002.00002.0000AID977610
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1811Experimentally measured binding affinity data derived from PDB2001Biochemistry, Feb-13, Volume: 40, Issue:6
Crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonate identifies the role of Glu357 in catalysis.
AID977610Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB2001Biochemistry, Feb-13, Volume: 40, Issue:6
Crystal structure of rabbit phosphoglucose isomerase complexed with 5-phospho-D-arabinonate identifies the role of Glu357 in catalysis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.06

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.06 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.26 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.06)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]