ammosamide A: structure in first source [MeSH]
| ID Source | ID |
|---|---|
| PubMed CID | 25172829 |
| CHEMBL ID | 4100877 |
| SCHEMBL ID | 261071 |
| MeSH ID | M0528859 |
| Synonym |
|---|
| SCHEMBL261071 |
| ammosamide a |
| CHEMBL4100877 |
| 9,11-diamino-10-chloro-2-methyl-3-sulfanylidene-2,7-diazatricyclo[6.3.1.04,12]dodeca-1(11),4,6,8(12),9-pentaene-6-carboxamide |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1437640 | Cytotoxicity against human HCT116 cells assessed as growth inhibition by MTS assay | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1 ISSN: 1520-6025 | Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. |
| AID1437645 | Antibacterial activity against Escherichia coli MG1655 at 10 ug after 48 hrs by disk diffusion method | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1 ISSN: 1520-6025 | Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. |
| AID1437641 | Cytotoxicity against human HCT116 cells assessed as growth inhibition at 78.125 ug/ml by MTS assay relative to control | 2017 | Journal of natural products, 01-27, Volume: 80, Issue:1 ISSN: 1520-6025 | Thiol-Based Probe for Electrophilic Natural Products Reveals That Most of the Ammosamides Are Artifacts. |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 5 (71.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| etoposide | beta-D-glucoside; furonaphthodioxole; organic heterotetracyclic compound | antineoplastic agent; DNA synthesis inhibitor | 2017 | 2017 | 7.0 | low | 0 | 0 | 0 | 0 | 1 | 0 | |
| ammosamide b | 2017 | 2017 | 7.0 | medium | 0 | 0 | 0 | 0 | 1 | 0 |
| Substance | Studies | Classes | Roles | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| carbostyril | monohydroxyquinoline; quinolone | bacterial xenobiotic metabolite | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 | |
| pyrroles | pyrrole; secondary amine | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 | ||
| 2-oxindole | gamma-lactam; indolinone | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 | ||
| pyrroloquinoline | 2016 | 2016 | 8.0 | low | 0 | 0 | 0 | 0 | 1 | 0 | |||
| ammosamide b | 2009 | 2016 | 13.0 | high | 0 | 0 | 0 | 4 | 2 | 0 |
| Condition | Indicated | Studies | First Year | Last Year | Average Age | Relationship Strength | Trials | pre-1990 | 1990's | 2000's | 2010's | post-2020 |
|---|