Compounds > alpha-bromo-beta-(5-imidazolyl)propionic acid
Page last updated: 2024-12-07

alpha-bromo-beta-(5-imidazolyl)propionic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID99855
CHEMBL ID3249829
SCHEMBL ID1395878
MeSH IDM0040408

Synonyms (22)

Synonym
35319-96-1
nsc240869
nsc-240869
2-bromo-3-(1h-imidazol-5-yl)propanoic acid
2-bromo-3-(1h-imidazol-4-yl)propanoic acid
dl-alpha-bromo-beta-(5-imidazoyl)propionic acid
alpha-bromo-beta-(5-imidazolyl)propionic acid
1h-imidazole-4-propanoic acid, alpha-bromo-, (+-)-
d,l-alpha-bromo-beta-(5-imidazolyl)propionic acid
nsc 240869
2-bromo-3-(5-imidazolyl)propionate
dl-alpha-bromo-beta-(5-imidazolyl)propionic acid
CHEMBL3249829
CRTWOYOCILXSSX-UHFFFAOYSA-N
alpha-bromo-beta-(5-imidazolyl) propionic acid
SCHEMBL1395878
dl-alpha-bromo-(5-imidazolyl)propionic acid
dl-a-bromo-ss-(5-imidazolyl)propionic acid
(r,s)-2-bromo-3-(5-imidazolyl)propionic acid
FT-0765604
dl-alpha-bromo-beta-(5-imidazolyl)propionicacid
SB46580
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID1133933Inhibition of histidine decarboxylase in Sprague-Dawley rat stomach assessed as decrease in 14CO2 production using L-histidine-carboxyl-14C as substrate at 0.10 mM by scintillation counting analysis1977Journal of medicinal chemistry, Apr, Volume: 20, Issue:4
Inhibition of histidine decarboxylase. Derivatives of histidine.
AID1135700Inhibition of Rana catesbeiana tadpole collagenase using lathyritic rat skin collagen as substrate after 41 hrs by radial diffusion assay1978Journal of medicinal chemistry, Jul, Volume: 21, Issue:7
Mercaptoimidazolylpropionic acid hydrobromide. Inhibition of tadpole collagenase and related properties.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-19909 (64.29)18.7374
1990's5 (35.71)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.66 (24.57)
Research Supply Index2.71 (2.92)
Research Growth Index4.37 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chloroacetaldehyde
[no description available]		1.9510organochlorine compound
1-propanol
1-Propanol: A colorless liquid made by oxidation of aliphatic hydrocarbons that is used as a solvent and chemical intermediate.. propan-1-ol : The parent member of the class of propan-1-ols that is propane in which a hydrogen of one of the methyl groups is replaced by a hydroxy group.		1.9910propan-1-ols;
short-chain primary fatty alcohol		metabolite;
protic solvent
disulfiram
[no description available]		1.9910organic disulfide;
organosulfur acaricide		angiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
EC 1.2.1.3 [aldehyde dehydrogenase (NAD(+))] inhibitor;
EC 3.1.1.1 (carboxylesterase) inhibitor;
EC 3.1.1.8 (cholinesterase) inhibitor;
EC 5.99.1.2 (DNA topoisomerase) inhibitor;
ferroptosis inducer;
fungicide;
NF-kappaB inhibitor
iodoacetic acid
Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.. iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.		2.3620haloacetic acid;
organoiodine compound		alkylating agent
sorbitol
D-glucitol : The D-enantiomer of glucitol (also known as D-sorbitol).		1.9910glucitolcathartic;
Escherichia coli metabolite;
food humectant;
human metabolite;
laxative;
metabolite;
mouse metabolite;
Saccharomyces cerevisiae metabolite;
sweetening agent
cysteine
[no description available]		1.9510cysteine zwitterion;
cysteine;
L-alpha-amino acid;
proteinogenic amino acid;
serine family amino acid		EC 4.3.1.3 (histidine ammonia-lyase) inhibitor;
flour treatment agent;
human metabolite
edetic acid
Edetic Acid: A chelating agent that sequesters a variety of polyvalent cations such as CALCIUM. It is used in pharmaceutical manufacturing and as a food additive.		1.9610ethylenediamine derivative;
polyamino carboxylic acid;
tetracarboxylic acid		anticoagulant;
antidote;
chelator;
copper chelator;
geroprotector
bromoacetate
[no description available]		1.9610carboxylic acid;
organohalogen compound
histidine
Histidine: An essential amino acid that is required for the production of HISTAMINE.. L-histidine : The L-enantiomer of the amino acid histidine.. histidine : An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3.		1.9510amino acid zwitterion;
histidine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
3-bromopropionic acid
[no description available]		1.9610
2-bromopropionic acid, (dl)-isomer
2-bromopropionic acid: RN given refers to cpd without isomeric designation		1.9610
acetylcysteine
N-acetyl-L-cysteine : An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.		1.9510acetylcysteine;
L-cysteine derivative;
N-acetyl-L-amino acid		antidote to paracetamol poisoning;
antiinfective agent;
antioxidant;
antiviral drug;
ferroptosis inhibitor;
geroprotector;
human metabolite;
mucolytic;
radical scavenger;
vulnerary
phenyl acetate
phenyl acetate: The ester formed between phenol and acetic acid. Don't confuse with phenylacetic acid derivatives listed under PHENYLACETATES.. phenyl acetate : An acetate ester obtained by the formal condensation of phenol with acetic acid.		1.9610benzenes;
phenyl acetates
1,7-phenanthroline
[no description available]		1.9610phenanthroline
5-imidazolepropionic acid
5-imidazolepropionic acid: competitive inhibitor of urocanase reaction which catalyzes conversion of urocanate into imidazolone propionate; structure. dihydrourocanic acid : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 3 has been replaced by an imidazol-4-yl group.		1.9510imidazoles;
monocarboxylic acid
n-acetylhistidine
N-acetylhistidine: RN given refers to (L)-isomer. N-acetylhistidine : A histidine derivative that is histidine in which one of the hydrogens of the alpha-amino group is substituted by an acetyl group.. N-acetyl-L-histidine : A histidine derivative that is L-histidine having an acetyl substituent on the alpha-nitrogen.		1.9510L-histidine derivative;
N-acetyl-L-amino acid;
N-acetylhistidine		animal metabolite
piperazine-n,n'-bis(2-ethanesulfonic acid)
piperazine-N,N'-bis(2-ethanesulfonic acid): RN given refers to parent cpd. 2,2'-piperazine-1,4-diylbisethanesulfonic acid : A Good's buffer substance, pKa = 6.8 at 20 degreeC.		1.9510PIPES
1-methylhistidine
1-methylhistidine: found in muscle proteins; RN given refers to (L)-isomer. 1-methylhistidine : A methylhistidine in which the methyl group is located at N-1.. N(tele)-methyl-L-histidine : A L-histidine derivative in which the methyl group is at N(tele)-position.		1.9510L-histidine derivative;
non-proteinogenic L-alpha-amino acid;
zwitterion		human metabolite
histidine methyl ester
histidine methyl ester: RN given refers to (L)-isomer; structure given in first source. histidine methyl ester : An alpha-amino acid ester that is the methyl ester of histidine.		1.9510histidine derivative
histidylglycine
histidylglycine: RN given refers to all (L)-isomer. His-Gly : A dipeptide formed from L-histidine and glycine residues.		1.9510dipeptidemetabolite
alpha-methylhistidine
alpha-methylhistidine : A non-proteinogenic alpha-amino acid that is histidine in which the methyl group is located at the Calpha-position.. alpha-methyl-L-histidine : An alpha-methylhistidine that has L-configuration.		1.9510alpha-methylhistidine
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		2.6730organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials