| Assay ID | Title | Year | Journal | Article |
|---|
| AID93720 | Inhibitory activity against Ionotropic glutamate receptor kainate using [3H]-kainic acid as radioligand | 1996 | Journal of medicinal chemistry, Jan-05, Volume: 39, Issue:1
| N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. |
| AID144826 | Inhibition of [3H]-MK-801 binding to EAA receptor sites in rat cortical membranes | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands. |
| AID144323 | The compound was evaluated for agonist activity at NMDA receptor in rat cortical wedge preparation | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID144611 | Compound was evaluated for its ability to displace [3H]Glu/[3H]-AP5 from rat brain membrane | 1992 | Journal of medicinal chemistry, Apr-17, Volume: 35, Issue:8
| Generation of N-methyl-D-aspartate agonist and competitive antagonist pharmacophore models. Design and synthesis of phosphonoalkyl-substituted tetrahydroisoquinolines as novel antagonists. |
| AID107254 | Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu6 | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID144465 | Agonistic activity at NMDA receptor of rat brain membrane using [3H]MK-801 as radioligand | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID175684 | Effective concentration in vitro as electropharmacological activity in the rat cortical wedge preparation | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands. |
| AID108656 | Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu1-alpha | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID144464 | Agonistic activity at NMDA receptor of rat brain membrane using [3H]CPP as radioligand | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID177860 | Effective dose against rat cortical slice cells using Electrophysiological experiment. | 1996 | Journal of medicinal chemistry, Jan-05, Volume: 39, Issue:1
| N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. |
| AID109483 | Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu4a; Not determined | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID92206 | Agonistic activity at Ionotropic glutamate receptor AMPA of rat brain membrane using [3H]AMPA as radioligand | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID221511 | Compound was evaluated for agonistic activity against mGluR1 alpha metabotropic receptor subtype in rat cortical slice model | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. |
| AID221676 | Compound was evaluated for agonistic activity against mGluR4a alpha metabotropic receptor subtype in rat cortical slice model | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. |
| AID144992 | Tested in vitro for the concentration required to inhibit [3H]CPP radioligand at EAA receptor sites in rat cortical membranes | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands. |
| AID31587 | Tested in vitro for the concentration required to inhibit [3H]AMPA radioligand at EAA receptor sites in rat cortical membranes | 1994 | Journal of medicinal chemistry, Sep-30, Volume: 37, Issue:20
| Synthesis and structure-activity studies on acidic amino acids and related diacids as NMDA receptor ligands. |
| AID221526 | Compound was evaluated for agonistic activity against mGluR2 alpha metabotropic receptor subtype in rat cortical slice model | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. |
| AID93725 | The compound was evaluated for agonist to competitive inhibition of radioligand ([3H]- kainic acid ) at Ionotropic glutamate receptor kainate | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| AID92499 | Inhibitory activity against Ionotropic glutamate receptor AMPA using [3H]AMPA as radioligand | 1996 | Journal of medicinal chemistry, Jan-05, Volume: 39, Issue:1
| N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. |
| AID144902 | Inhibitory activity against N-methyl-D-aspartate glutamate receptor using [3H]CPP as radioligand | 1996 | Journal of medicinal chemistry, Jan-05, Volume: 39, Issue:1
| N-methyl-D-aspartic acid receptor agonists: resolution, absolute stereochemistry, and pharmacology of the enantiomers of 2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. |
| AID175695 | Evaluated for effective concentration in, in vitro electrophysiological model in the rat cortical slice model. | 1998 | Bioorganic & medicinal chemistry letters, Jun-16, Volume: 8, Issue:12
| Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid. |
| AID109010 | Agonist activity of the compound at Metabotropic Excitatory Amino acid Receptors Expressed in CHO cells. mGlu2 | 1996 | Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
| A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |