alantrypinone: a Penicillium alkaloid; a tricyclic pyrazinoquinazolinedione base bridged by a 3-methyleneoxindole substructure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 10666980 |
| MeSH ID | M0297475 |
| Synonym |
|---|
| 212911-06-3 |
| alantrypinone |
| (1'r,3r,12'r)-12'-methylspiro[1h-indole-3,16'-2,10,13-triazatetracyclo[10.2.2.02,11.04,9]hexadeca-4,6,8,10-tetraene]-2,3',14'-trione |
| (1's,3s,12's)-12'-methyl-3'h,15'h-spiro[indole-3,13'-[2,10,16]triazatetracyclo[10.2.2.02,11.04,9]hexadeca[4,6,8,10]tetraene]-2,3',15'(1h)-trione |
| DTXSID70891846 |
| Q63392384 |
Alantrypinone is an insecticidal alkaloid that acts as a selective antagonist for housefly (vs rat) GABA receptors. It is considered to be a lead compound for the development of a safer insecticide.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Alantrypinone is an insecticidal alkaloid that acts as a selective antagonist for housefly (vs rat) GABA receptors, and is considered to be a lead compound for the development of a safer insecticide." | ( Alantrypinone and its derivatives: synthesis and antagonist activity toward insect GABA receptors. Alam, MS; Arisawa, M; Mitomi, M; Narusuye, K; Nishida, A; Ozoe, Y; Watanabe, T; Yamamoto, K, 2009) | 2.52 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||