Compounds > akuammine
Page last updated: 2024-11-10

akuammine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

akuammine: from the seeds of Picralima nitida; has affinity for opioid receptors; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
Picralimagenus[no description available]ApocynaceaeThe dogbane family of the order Gentianales. Members of the family have milky, often poisonous juice, smooth-margined leaves, and flowers in clusters.[MeSH]

Cross-References

ID SourceID
PubMed CID13491909
MeSH IDM0201656

Synonyms (14)

Synonym
unii-0421aqv5w3
0421aqv5w3 ,
3512-87-6
akuammine
vincamajoridine
(-)-akuammine
akuammin
vincamajoridin
akuammine [mi]
2h,12h-12a,2,7a-(epoxyethanylylidene)indolo(2,3-a)quinolizine-15-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-9-hydroxy-12-methyl-, methyl ester, (2s,3e,7as,12as,12bs,15r)-
2h,12h-12a,2,7a-(epoxyethanylylidene)indolo(2,3-a)quinolizine-15-carboxylic acid, 3-ethylidene-1,3,4,6,7,12b-hexahydro-9-hydroxy-12-methyl-, methyl ester, (2s-(2.alpha.,3e,7a.alpha.,12a.alpha.,12b.beta.,15s*))-
DTXSID401018404
methyl (1s,9s,14e,15s,16r,19s)-14-ethylidene-6-hydroxy-2-methyl-18-oxa-2,12-diazahexacyclo[13.3.2.01,9.03,8.09,16.012,19]icosa-3(8),4,6-triene-16-carboxylate
AKOS040746515
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (16.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's1 (16.67)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
raubasine
raubasine: RN given refers to (19alpha)-isomer; structure		2.6320yohimban alkaloid
akuammicine
akuammicine: from Strychnos sp;; structure in first source. akuammicine : A monoterpenoid indole alkaloid with formula C20H22N2O2, isolated from several plant species including Alstonia spatulata, Catharanthus roseus and Vinca major.		2.3110methyl ester;
monoterpenoid indole alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		plant metabolite
strictamine
strictamine: structure		2.1710
ConditionIndicatedRelationship StrengthStudiesTrials