Assay ID | Title | Year | Journal | Article |
AID15338 | Concentration 1 detected in blood of rat 1 hr after an oral dose of 200 mg/kg of the compound; ND is Not Detected. | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID188661 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an intraperitoneal dose of 25 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID188674 | Gastroprotective activity on stress-induced ulcers in male Wistar rats at 6.25 mg/kg upon intraperitoneal administration | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon |
AID188669 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an oral dose of 25 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID188667 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an oral dose of 12.5 mg/kg; NT is Not tested. | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID117092 | Lethal dose in mice upon intraperitoneal administration;Value ranges from(131.6-243.4) | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon |
AID188658 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an intraperitoneal dose of 12.5 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID15365 | Concentration detected in blood of rat 3 hr after an oral dose of 200 mg/kg; ND is Not Detected | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID1298881 | Anti-ulcer activity in Sprague-Dawley rat stomach assessed as protection against stress-induced gastric ulcer at 25 mg/kg, po pretreated for 30 mins followed by stress measured after 6 hrs relative to control | 2016 | European journal of medicinal chemistry, Jun-30, Volume: 116 | Isocoumarins, miraculous natural products blessed with diverse pharmacological activities. |
AID188671 | Gastroprotective activity on stress-induced ulcers in male Wistar rats at 12.5 mg/kg upon intraperitoneal administration | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon |
AID188672 | Gastroprotective activity on stress-induced ulcers in male Wistar rats at 25 mg/kg upon intraperitoneal administration | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon |
AID188673 | Gastroprotective activity on stress-induced ulcers in male Wistar rats at 50 mg/kg upon intraperitoneal administration | 1983 | Journal of medicinal chemistry, Oct, Volume: 26, Issue:10
| 1H-2-benzopyran-1-one derivatives, microbial products with pharmacological activity. Relationship between structure and activity in 6-[[1(S)-(3(S),4- dihydro-8-hydroxy-1-oxo-1H-2-benzopyran-3-yl)-3-methylbutyl]-amino]-4(S), 5(S)-dihydroxy-6-oxo-3(S)-ammon |
AID188662 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an intraperitoneal dose of 50 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID20323 | % recovery from whole blood of 7 wistar rats after an oral dose of the compound | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID188670 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an oral dose of 50 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
AID188663 | Gastroprotective activity as % protection against stress ulcers in 5 rats after an oral dose of 100 mg/kg | 1985 | Journal of medicinal chemistry, Jan, Volume: 28, Issue:1
| 1H-2-Benzopyran-1-one derivatives, microbial products with pharmacological activity. Conversion into orally active derivatives with antiinflammatory and antiulcer activities. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |