| Assay ID | Title | Year | Journal | Article |
|---|
| AID162575 | The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF) | 2003 | Journal of medicinal chemistry, Sep-25, Volume: 46, Issue:20
| SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase. |
| AID610958 | Inhibition of PARG using [alpha-32P]ADP-ribose polymers after 5 mins by TRAP assay | 2011 | Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
| Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG). |
| AID162266 | Inhibitor dissociation constant was determined by the analysis of the slope versus [inhibitor] replot.e.K | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID162264 | Kid describes the approach of hyperbolic function to its new limiting value as [I] increases, for the KM/V vs [I] replot. | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID31125 | Inhibition of ADP-ribosyltransferase 1 that catalyze ADP-ribosyltransferase was measured at 100 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID162391 | Inhibition of Poly (ADP-ribose) polymerase that catalyze ADP-ribosyltransferase was measured at 1000 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID162263 | Kid describes the approach of hyperbolic function to its new limiting value as [I] increases, for the 1/V vs [I] replot. | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID162389 | Inhibition of Poly (ADP-ribose) polymerase that catalyze ADP-ribosyltransferase was measured at 0 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID144370 | Compound was tested for its inhibitory activity against venom NAD glycohydrolase | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID144371 | Compound was tested for the inhibitor activity against NAD glycohydrolase. | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID162390 | Inhibition of Poly (ADP-ribose) polymerase that catalyze ADP-ribosyltransferase was measured at 100 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID225939 | The compound was tested for its ability to inhibit bovine thymus polyadenosine diphosphoribose glycohydrolase (bPARG) | 2003 | Journal of medicinal chemistry, Sep-25, Volume: 46, Issue:20
| SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase. |
| AID31124 | Inhibition of ADP-ribosyltransferase 1 that catalyze ADP-ribosyltransferase was measured at 0 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID31126 | Inhibition of ADP-ribosyltransferase 1 that catalyze ADP-ribosyltransferase was measured at 1000 uM concentration | 1995 | Journal of medicinal chemistry, Jan-20, Volume: 38, Issue:2
| Specific inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID610957 | Inhibition of PARP-1 using [32P]-NAD+ after 15 mins | 2011 | Journal of medicinal chemistry, Aug-11, Volume: 54, Issue:15
| Discovery and structure-activity relationships of modified salicylanilides as cell permeable inhibitors of poly(ADP-ribose) glycohydrolase (PARG). |
| AID1184468 | Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay | 2014 | Bioorganic & medicinal chemistry letters, Aug-15, Volume: 24, Issue:16
| Design and synthesis of phenolic hydrazide hydrazones as potent poly(ADP-ribose) glycohydrolase (PARG) inhibitors. |
| AID162574 | The compound was tested for its ability to inhibit recombinant bovine polyadenosine diphosphoribose glycohydrolase catalytic fragment (rPARG-CF) | 2003 | Journal of medicinal chemistry, Sep-25, Volume: 46, Issue:20
| SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase. |
| AID162265 | Inhibitor dissociation constant for the 1/V vs [I] replot. | 1995 | Journal of medicinal chemistry, Oct-13, Volume: 38, Issue:21
| Mechanism of inhibition of poly(ADP-ribose) glycohydrolase by adenosine diphosphate (hydroxymethyl)pyrrolidinediol. |
| AID225940 | The compound was tested for its ability to inhibit bovine thymus polyadenosine diphosphoribose glycohydrolase (bPARG) | 2003 | Journal of medicinal chemistry, Sep-25, Volume: 46, Issue:20
| SAR analysis of adenosine diphosphate (hydroxymethyl)pyrrolidinediol inhibition of poly(ADP-ribose) glycohydrolase. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |