Assay ID | Title | Year | Journal | Article |
AID1284142 | Inhibition of Xenopus laevis kinesin-5 assessed as velocity at 150 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 17.2 +/- 8.3 nm/s) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1228728 | Antiviral activity against Sindbis virus strain HRsp infected in african green monkey Vero cells assessed as inhibition of virus induced cell death measured after 7 days | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1284138 | Inhibition of Xenopus laevis kinesin-5 assessed as attachment to microtubules incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284135 | Cytotoxicity against mouse L929 cells after 5 days by MTT assay | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284163 | Inhibition of eGFP-tagged rat kinesin-1 assessed as velocity at 300 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 535.7 +/- 35.7 nm/s) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1540945 | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 1 hr by MTT assay | | | |
AID1284152 | Inhibition of Xenopus laevis kinesin-5 assessed as motile protein molecules at 300 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 42.81 +/- 0.25%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284144 | Inhibition of Xenopus laevis kinesin-5 assessed as velocity at 600 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 17.2 +/- 8.3 nm/s) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1228730 | Cytotoxicity against african green monkey Vero cells assessed as inhibition of cell metabolism after 72 hrs by MTS assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1284151 | Inhibition of Xenopus laevis kinesin-5 assessed as motile protein molecules at 150 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 42.81 +/- 0.25%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1228739 | Cytotoxicity against human HCT116 cells at 1 uM after 72 hrs by MTS assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1228727 | Antiviral activity against Chikungunya virus strain 899 infected in african green monkey Vero cells assessed as inhibition of virus induced cell death measured after 7 days | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1284150 | Inhibition of Xenopus laevis kinesin-5 assessed as relative number of MT-bound proteins at 600 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 100 +/- 0.9%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284170 | Inhibition of eGFP-tagged rat kinesin-1 assessed as relative number of MT-bound proteins at 600 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 100 +/- 1.8%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284164 | Inhibition of eGFP-tagged rat kinesin-1 assessed as velocity at 600 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 535.7 +/- 35.7 nm/s) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1484124 | Antiproliferative activity against human A498 cells after 48 hrs by MTT assay | 2017 | Journal of natural products, 03-24, Volume: 80, Issue:3
| Englerins: A Comprehensive Review. |
AID1284139 | Inhibition of Xenopus laevis kinesin-5 assessed as decrease in protein molecules per micrometer microtubule length for 7 mins measured for 600 secs by single molecule TIRF microscopy | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284134 | Antiproliferative activity against human U937 cells after 5 days by MTT assay | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1301140 | Activation of PKC in human 786-0 cells at 1 uM | 2016 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 26, Issue:11
| Synthesis of a stable and orally bioavailable englerin analogue. |
AID1284169 | Inhibition of eGFP-tagged rat kinesin-1 assessed as relative number of MT-bound proteins at 300 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 100 +/- 1.8%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284148 | Inhibition of Xenopus laevis kinesin-5 assessed as relative number of MT-bound proteins at 150 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 100 +/- 0.9%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284167 | Inhibition of eGFP-tagged rat kinesin-1 assessed as attachment frequency at 300 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 7.72 +/- 0.31 /microM/micrometer/sec) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284166 | Inhibition of eGFP-tagged rat kinesin-1 assessed as attachment frequency at 600 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 7.72 +/- 0.31 /microM/micrometer/sec) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1228740 | Cytotoxicity against human MCF7 cells at 1 uM after 72 hrs by MTS assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1228729 | Antiviral activity against Semliki forest virus strain Vietnam infected in african green monkey Vero cells assessed as inhibition of virus induced cell death measured after 7 days | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1284174 | Cytotoxicity against Potorous tridactylus PtK2 cells assessed as effect on phenotype of interphase cell at 21.5 uM after 18 hrs by DAPI staining-based fluorescence microscopy | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284147 | Inhibition of Xenopus laevis kinesin-5 assessed as attachment frequency at 600 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 1.08 +/- 0.10 /microM/micrometer/sec) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284143 | Inhibition of Xenopus laevis kinesin-5 assessed as velocity at 300 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 17.2 +/- 8.3 nm/s) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1228741 | Cytotoxicity against human PC3 cells at 1 uM after 72 hrs by MTS assay | 2015 | Journal of natural products, May-22, Volume: 78, Issue:5
| Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata. |
AID1284173 | Inhibition of eGFP-tagged rat kinesin-1 assessed as motile protein molecules at 600 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 88.74 +/- 0.34%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284172 | Inhibition of eGFP-tagged rat kinesin-1 assessed as motile protein molecules at 300 uM incubated for 7 mins measured for 60 secs by single molecule TIRF microscopy (Rvb = 88.74 +/- 0.34%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284149 | Inhibition of Xenopus laevis kinesin-5 assessed as relative number of MT-bound proteins at 300 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 100 +/- 0.9%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284136 | Cytotoxicity against Potorous tridactylus PtK2 cells after 5 days by MTT assay | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284153 | Inhibition of Xenopus laevis kinesin-5 assessed as motile protein molecules at 600 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 42.81 +/- 0.25%) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284137 | Cell cycle arrest in Potorous tridactylus PtK2 cells assessed as unphysiological monoastral half spindle formation at 21.5 uM after 18 hrs by DAPI staining-based fluorescence microscopy | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284146 | Inhibition of Xenopus laevis kinesin-5 assessed as attachment frequency at 300 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 1.08 +/- 0.10 /microM/micrometer/sec) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
AID1284145 | Inhibition of Xenopus laevis kinesin-5 assessed as attachment frequency at 150 uM incubated for 7 mins measured for 600 secs by single molecule TIRF microscopy (Rvb = 1.08 +/- 0.10 /microM/micrometer/sec) | 2016 | European journal of medicinal chemistry, Apr-13, Volume: 112 | The natural diterpene tonantzitlolone A and its synthetic enantiomer inhibit cell proliferation and kinesin-5 function. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |