Page last updated: 2024-12-08
Echinocystic acid 3-glucoside
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
ecliptasaponin A: has anti-fibrotic activity; isolated from Ecliptae Herba extract; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 476537 |
| CHEMBL ID | 3343916 |
| CHEBI ID | 184046 |
Synonyms (26)
| Synonym |
|---|
| (4ar,5r,6ar,6as,6br,8ar,10s,12ar,14bs)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
| echinocystic acid 3-o-.beta.-d-glucopyranoside |
| 78285-90-2 |
| echinocystic acid 3-glucoside |
| (4ar,5r,6ar,6as,6br,8ar,10s,12ar,14bs)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
| CHEBI:184046 |
| A839703 |
| (4ar,5r,6ar,6as,6br,8ar,10s,12ar,14bs)-10-[(2r,3r,4s,5s,6r)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-5-oxidanyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
| (4ar,5r,6ar,6as,6br,8ar,10s,12ar,14bs)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)-2-oxanyl]oxy]-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid |
| S9403 |
| echinocystic acid-3-o-glucoside |
| AC-34295 |
| eclalbasaponin ii |
| ecliptasaponin a |
| mfcd00017386 |
| CHEMBL3343916 |
| eclalbasaponin ii, analytical standard |
| gleditsoside b |
| gleditschoside b |
| CS-0017051 |
| HY-N1508 |
| CCG-270299 |
| DTXSID10999638 |
| olean-12-en-28-oic acid, 3-(b-d-glucopyranosyloxy)-16-hydroxy-,(3b,16a)- |
| echinocysticacid-3-glucoside |
| AKOS040750442 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Drug Classes (1)
| Class | Description |
|---|---|
| triterpenoid saponin | A terpene glycoside in which the terpene moiety is a triterpenoid. |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
Bioassays (4)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1172861 | Inhibition of NFkappaB (unknown origin) expressed in in LPS-stimulated HEK293-NF-kappaB-luc cells assessed as luminescence signals measured by relative light units at 500 ug/mL pre-treated for 4 hrs before LPS challenge for 24 hrs by luciferase assay | 2014 | Bioorganic & medicinal chemistry, Nov-15, Volume: 22, Issue:22 | Thiophenes, polyacetylenes and terpenes from the aerial parts of Eclipata prostrate. |
| AID1172858 | Inhibition of NFkappaB (unknown origin) expressed in in LPS-stimulated HEK293-NF-kappaB-luc cells assessed as luminescence signals measured by relative light units at 1 ug/mL pre-treated for 4 hrs before LPS challenge for 24 hrs by luciferase assay | 2014 | Bioorganic & medicinal chemistry, Nov-15, Volume: 22, Issue:22 | Thiophenes, polyacetylenes and terpenes from the aerial parts of Eclipata prostrate. |
| AID1172860 | Inhibition of NFkappaB (unknown origin) expressed in in LPS-stimulated HEK293-NF-kappaB-luc cells assessed as luminescence signals measured by relative light units at 100 ug/mL pre-treated for 4 hrs before LPS challenge for 24 hrs by luciferase assay | 2014 | Bioorganic & medicinal chemistry, Nov-15, Volume: 22, Issue:22 | Thiophenes, polyacetylenes and terpenes from the aerial parts of Eclipata prostrate. |
| AID1172859 | Inhibition of NFkappaB (unknown origin) expressed in in LPS-stimulated HEK293-NF-kappaB-luc cells assessed as luminescence signals measured by relative light units at 10 ug/mL pre-treated for 4 hrs before LPS challenge for 24 hrs by luciferase assay | 2014 | Bioorganic & medicinal chemistry, Nov-15, Volume: 22, Issue:22 | Thiophenes, polyacetylenes and terpenes from the aerial parts of Eclipata prostrate. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (7)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.25
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.25) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 7 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||