9,10-epoxystearic acid

Description

9,10-Epoxystearic acid (ESA) is a fatty acid epoxide derived from oleic acid. It is a naturally occurring compound found in small amounts in various plant and animal sources. ESA can be synthesized via epoxidation of oleic acid using various reagents such as peracids or hydrogen peroxide. ESA exhibits several biological effects, including anti-inflammatory, anticancer, and antimicrobial activities. It has been shown to inhibit the growth of certain cancer cell lines and possesses promising potential as a therapeutic agent for inflammatory diseases. The unique structure of ESA, with its epoxide group, plays a crucial role in its biological activity. The epoxide ring can undergo ring-opening reactions, leading to the formation of various derivatives with different biological properties. The study of ESA is driven by its potential therapeutic applications and its role in understanding the complex biological pathways involving fatty acid epoxides. '

9,10-epoxystearic acid: RN given refers to parent cpd with unspecified isomeric designation; structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

9,10-epoxyoctadecanoic acid : An epoxy fatty acid consisting of octadecanoic (stearic) acid with a single epoxide located between positions 9 and 10. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]