Assay ID | Title | Year | Journal | Article |
AID24208 | Association constant for binding to poly [d(A-T)] | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID116415 | Maximum percent increase in life span of mice was determined by L1210 assay | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID210614 | Compound concentration in mole/kg/day lethal to 10% of mice | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Potential antitumor agents. 36. Quantitative relationships between experimental antitumor activity, toxicity, and structure for the general class of 9-anilinoacridine antitumor agents. |
AID25559 | Ionization constant (pKa) | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Potential antitumor agents. 36. Quantitative relationships between experimental antitumor activity, toxicity, and structure for the general class of 9-anilinoacridine antitumor agents. |
AID100307 | Dose of the drug (mol /kg) providing a 50% life extension in L1210 assays when given at qd 1-5 schedule; No data | 1987 | Journal of medicinal chemistry, Mar, Volume: 30, Issue:3
| Redox chemistry of the 9-anilinoacridine class of antitumor agents. |
AID46149 | Inhibitory concentration against ethidium binding to DNA | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID116709 | Drug dose that is lethal to 10% of animals was measured | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID26375 | Ionisation constant (pKa) | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID24209 | Association constant for binding to poly [d(G-C)] | 1981 | Journal of medicinal chemistry, Feb, Volume: 24, Issue:2
| Potential antitumor agents. 34. Quantitative relationships between DNA binding and molecular structure for 9-anilinoacridines substituted in the anilino ring. |
AID97604 | Tumor cell selectivity determined as maximal percent increase in life span (ILSmax) at LD10 dosage level in L1210 cells | 1982 | Journal of medicinal chemistry, Aug, Volume: 25, Issue:8
| Structure-antitumor activity relationships of 9-anilinoacridines using pattern recognition. |
AID98491 | Inhibitory concentration to reduce the growth of L1210 cells by 50% after 70 h; No data | 1987 | Journal of medicinal chemistry, Mar, Volume: 30, Issue:3
| Redox chemistry of the 9-anilinoacridine class of antitumor agents. |
AID98819 | Drug concentration in mole/kg/day providing 50% extension of life in intraperitoneally implanted leukemia L1210 mice. | 1982 | Journal of medicinal chemistry, Mar, Volume: 25, Issue:3
| Potential antitumor agents. 36. Quantitative relationships between experimental antitumor activity, toxicity, and structure for the general class of 9-anilinoacridine antitumor agents. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |