Page last updated: 2024-12-11

9-(3-oxoprop-1-enyl)adenine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

9-(3-oxoprop-1-enyl)adenine: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID6439040
CHEMBL ID176837
SCHEMBL ID2560690
MeSH IDM0227862

Synonyms (12)

Synonym
2-propenal, 3-(6-amino-9h-purin-9-yl)-
9-(3-oxoprop-1-enyl)adenine
adenine propenal
3-(6-amino-9h-purin-9-yl)-2-propenal
CHEMBL176837
(e)-3-(6-aminopurin-9-yl)prop-2-enal
AKOS006274731
90029-73-5
ccris 8712
SCHEMBL2560690
(2e)-3-(6-amino-9h-purin-9-yl)prop-2-enal
3-(6-amino-9h-purin-9-yl)acrylaldehyde
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (6)

Assay IDTitleYearJournalArticle
AID88670Inhibition of macromolecular synthesis in HeLa cells assayed by the incorporation of radioactive leucine into protein1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
AID88672Inhibition of macromolecular synthesis in HeLa cells assayed by the incorporation of radioactive uridine into RNA1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
AID22174Compound was evaluated for its half-life when nucleophile was added in solution buffered at pH 7.2 in the presence of glutathione1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
AID22173Compound was evaluated for its half-life when nucleophile was added in solution buffered at pH 7.2 in the presence of aminoethanol1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
AID88671Inhibition of macromolecular synthesis in HeLa cells assayed by the incorporation of radioactive thymidine into DNA1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
AID88705Inhibition of HeLa cells growth (cytotoxicity)1984Journal of medicinal chemistry, Aug, Volume: 27, Issue:8
Synthesis and biological activity of a new class of cytotoxic agents: N-(3-oxoprop-1-enyl)-substituted pyrimidines and purines.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's3 (42.86)18.2507
2000's1 (14.29)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.82 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.90 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]