8-oxo-dGMP : A purine 2'-deoxyribonucleoside 5'-monophosphate having 8-oxo-7,8-dihydroguanine as the nucleobase. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
ID Source | ID |
---|---|
PubMed CID | 135488904 |
CHEBI ID | 63223 |
SCHEMBL ID | 2388172 |
MeSH ID | M0175197 |
Synonym |
---|
8-oxo-2'-deoxy-guanosine-5'-monophosphate |
8OG , |
1PUN |
1PPX |
8-oxo-2'-deoxyguanosine-5'-monophosphate |
1PUS |
8-hydroxydeoxyguanosine 5'-monophosphate |
1PUQ |
8-oh-dgmp |
DB02023 |
2'-deoxy-7,8-dihydro-8-oxoguanosine 5'-monophosphate |
2'-deoxy-7,8-dihydro-8-oxo-5'-guanylic acid |
8-oxo-dgmp |
8-oxo-7,8-dihydro-2'-deoxy-guanosine-5'-monophosphate |
[(2r,3s,5r)-5-(2-amino-6,8-dioxo-3,7-dihydropurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate |
2'-deoxy-7,8-dihydro-8-oxo-5'-guanylate |
C19968 |
5'-guanylic acid, 2'-deoxy-7,8-dihydro-8-oxo- |
127027-50-3 |
CHEBI:63223 |
2'-deoxy-8-oxo-7,8-dihydroguanosine 5'-(dihydrogen phosphate) |
8-oxo-7,8-di-hydro-2' -deoxyguanosine-5' -monophosphate |
SCHEMBL2388172 |
[(2r,3s,5r)-5-(2-amino-6,8-dioxo-1,7-dihydropurin-9-yl)-3-hydroxyoxolan-2-yl]methyl dihydrogen phosphate |
8-hydroxydeoxy-guanosine 5'-monophosphate |
2'-deoxy-8-oxoguanosine 5'-(dihydrogen phosphate) |
9-(2-deoxy-5-o-phosphonopentofuranosyl)-2-imino-3,9-dihydro-2h-purine-6,8-diol |
DTXSID40925768 |
Q27132489 |
((2r,3s,5r)-5-(2-amino-6,8-dioxo-7,8-dihydro-3h-purin-9(6h)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl dihydrogen phosphate |
PD060155 |
{[(2r,3s,5r)-5-(2-amino-6,8-dioxo-6,7,8,9-tetrahydro-3h-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid |
Class | Description |
---|---|
purine 2'-deoxyribonucleoside 5'-monophosphate | |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
---|---|---|---|---|---|---|---|
Chain A, Mutator mutT protein | Escherichia coli | Kd | 0.0520 | 0.0520 | 0.0520 | 0.0520 | AID977611 |
Chain A, Mutator mutT protein | Escherichia coli | Kd | 0.0520 | 0.0520 | 0.0520 | 0.0520 | AID977611 |
Chain A, Mutator mutT protein | Escherichia coli | Kd | 0.0520 | 0.0520 | 0.0520 | 0.0520 | AID977611 |
Chain A, Mutator mutT protein | Escherichia coli | Kd | 0.0520 | 0.0520 | 0.0520 | 0.0520 | AID977611 |
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] |
Assay ID | Title | Year | Journal | Article |
---|---|---|---|---|
AID1811 | Experimentally measured binding affinity data derived from PDB | 2003 | Biochemistry, Sep-02, Volume: 42, Issue:34 | Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product. |
AID977611 | Experimentally measured binding affinity data (Kd) for protein-ligand complexes derived from PDB | 2003 | Biochemistry, Sep-02, Volume: 42, Issue:34 | Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Timeframe | Studies, This Drug (%) | All Drugs % |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (25.00) | 18.2507 |
2000's | 3 (75.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Publication Type | This drug (%) | All Drugs (%) |
---|---|---|
Trials | 0 (0.00%) | 5.53% |
Reviews | 1 (20.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 4 (80.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |