Page last updated: 2024-12-10

8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin: serotonin receptor agonist; structure & RN given in first source; RN given refers to HCL [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3082556
CHEMBL ID541095
MeSH IDM0152755

Synonyms (9)

Synonym
8-hydroxy-1-methyl-dpat
1-naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-8-methyl-, hydrochloride, (7s-cis)-
110312-35-1
8-hydroxy-1-methyl-2-(di-n-propylamino)tetralin
8-hmpat
chembl541095 ,
DTXSID80149209
(7s,8r)-7-(dipropylamino)-8-methyl-5,6,7,8-tetrahydronaphthalen-1-ol;hydrochloride
1-naphthalenol, 7-(dipropylamino)-5,6,7,8-tetrahydro-8-methyl-, hydroc hloride, (7s-cis)-
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (2)

Assay IDTitleYearJournalArticle
AID4225Binding affinity at 5-hydroxytryptamine 1A receptor by the displacement of [3H]8-OH-DPAT in rat brain.1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
A 3-D model for 5-HT1A-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin.
AID176731Dose corresponding to half-maximal decrease of 5-HTP formation in the limbic and striatal parts of rat brain1991Journal of medicinal chemistry, Feb, Volume: 34, Issue:2
A 3-D model for 5-HT1A-receptor agonists based on stereoselective methyl-substituted and conformationally restricted analogues of 8-hydroxy-2-(dipropylamino)tetralin.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (8)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (50.00)18.7374
1990's3 (37.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.96

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.96 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.16 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.96)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]