| Assay ID | Title | Year | Journal | Article |
|---|
| AID152226 | Binding affinity was determined towards opioid receptor mu1 using [3H]DAMGO as radioligand | 2003 | Bioorganic & medicinal chemistry letters, Jun-02, Volume: 13, Issue:11
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 2: 8-formamidocyclazocine analogues. |
| AID739876 | Partial agonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins by liquid scintillation counting | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID310353 | Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cells | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC. |
| AID270236 | Antagonist activity against human kappa opioid receptor expressed in CHO cells assessed as inhibition of U50488-stimulated [35S]GTP-gamma-S binding | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID739875 | Partial agonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins by liquid scintillation counting relative to control | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID270235 | Antagonist activity against human mu opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-stimulated [35S]GTPgammaS binding | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID270237 | Antagonist activity against human delta opioid receptor expressed in CHO cells assessed as inhibition of SNC80-stimulated [35S]GTP-gamma-S binding | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID739874 | Agonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS binding after 60 mins by liquid scintillation counting | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID149920 | Displacement of [3H]naltrindole from Opioid receptor delta 1 of guinea pig brain membranes | 2001 | Bioorganic & medicinal chemistry letters, Mar-12, Volume: 11, Issue:5
| 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines. |
| AID270234 | Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID310354 | Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cells | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC. |
| AID270233 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID270232 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID739877 | Partial agonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS binding after 60 mins by liquid scintillation counting relative to control | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID385256 | Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine. |
| AID739878 | Partial agonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS binding after 60 mins by liquid scintillation counting | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID149419 | Displacement of [3H]U-69593 from Opioid receptor kappa 1 of guinea pig brain membranes | 2001 | Bioorganic & medicinal chemistry letters, Mar-12, Volume: 11, Issue:5
| 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines. |
| AID385255 | Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine. |
| AID310352 | Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cells | 2007 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 17, Issue:23
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC. |
| AID148053 | Displacement of [3H]DAMGO from Opioid receptor mu 1 of guinea pig brain membranes | 2001 | Bioorganic & medicinal chemistry letters, Mar-12, Volume: 11, Issue:5
| 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines. |
| AID739872 | Antagonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as inhibition of U50,488-induced [35S]GTPgammaS binding after 60 mins by liquid scintillation counting | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID270242 | Antinociceptive activity in mouse at 1 mg/kg, ip | 2006 | Journal of medicinal chemistry, Sep-07, Volume: 49, Issue:18
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine. |
| AID385257 | Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells | 2008 | Bioorganic & medicinal chemistry, May-15, Volume: 16, Issue:10
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine. |
| AID739873 | Agonist activity at human kappa opioid receptor expressed in CHO cell membrane assessed as stimulation of [35S]GTPgammaS binding after 60 mins by liquid scintillation counting relative to control | 2013 | Bioorganic & medicinal chemistry letters, Apr-01, Volume: 23, Issue:7
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 9: Synthesis, characterization and molecular modeling of pyridinyl isosteres of N-BPE-8-CAC (1), a high affinity ligand for opioid receptors. |
| AID149266 | Binding affinity was determined towards opioid receptor kappa 1 using [3H]U-69593 as radioligand | 2003 | Bioorganic & medicinal chemistry letters, Jun-02, Volume: 13, Issue:11
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 2: 8-formamidocyclazocine analogues. |
| AID149901 | Binding affinity was determined towards Opioid receptor delta 1 using [3H]naltrindole as radioligand | 2003 | Bioorganic & medicinal chemistry letters, Jun-02, Volume: 13, Issue:11
| Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 2: 8-formamidocyclazocine analogues. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |