Page last updated: 2024-10-15

7-methylguanosine-5'-monophosphate

Description

7-methylguanosine 5'-phosphate(1-) : An organophosphate oxoanion arising from deprotonation of the phosphate OH groups of 7-methylguanosine 5'-phosphate; major species at pH 7.3. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID135563646
CHEBI ID58285
MeSH IDM0058570

Synonyms (14)

Synonym
7-methyl-5'-o-phosphonatoguanosine
CHEBI:58285
7-methylguanosine 5'-phosphate anion
7-methylguanosine 5'-phosphate(1-)
n(7)-methyl-gmp
7-methylguanosine-5'-phosphate
n7-methylguanosine 5'-phosphate
n7-methyl-guanosine-phosphate
n7-methyl-guanosine-5'-phosphate
7-methyl gmp
7-methylguanosine-5'-monophosphate
1h-purinium, 2-amino-6,9-dihydro-7-methyl-6-oxo-9-(5-o-phosphono-beta-d-ribofuranosyl)-, inner salt
3EVF
Q27125670
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
organophosphate oxoanionAn organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Inhibition Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Chain A, RNA-directed RNA polymerase NS5Yellow fever virus 17DKi0.17000.17000.17000.1700AID977610
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (1)

Assay IDTitleYearJournalArticle
AID977610Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB2009Journal of molecular biology, Feb-06, Volume: 385, Issue:5
Analysis of flavivirus NS5 methyltransferase cap binding.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (32)

TimeframeStudies, This Drug (%)All Drugs %
pre-199020 (62.50)18.7374
1990's5 (15.63)18.2507
2000's3 (9.38)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (6.06%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other31 (93.94%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]