| Assay ID | Title | Year | Journal | Article |
|---|
| AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
| AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
| AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
| AID315164 | Cytotoxicity against human U937 cells by trypan blue assay after 48 hrs | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells. |
| AID1441750 | Inhibition of full length recombinant human ALDH3A1 expressed in Escherichia coli BL21(DE3) assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in pr | | | |
| AID1781227 | Inhibition of Infectious hematopoietic necrosis virus glycoprotein G assessed as antiviral activity at 25 uM measured by RT-qPCR method relative to control | 2021 | European journal of medicinal chemistry, Nov-05, Volume: 223 | Synthesis and biological evaluation of novel coumarin derivatives in rhabdoviral clearance. |
| AID34983 | Compound was tested for percent inhibition at 10 e-4 M against rat lens aldose reductase | 1986 | Journal of medicinal chemistry, Jun, Volume: 29, Issue:6
| Synthesis and rat lens aldose reductase inhibitory activity of some benzopyran-2-ones. |
| AID315168 | Induction of apoptosis in human U937 cells at 250 uM after 24 hrs | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells. |
| AID315165 | Growth inhibition of human U937 cells by [3H]thymidine incorporation assay | 2008 | Bioorganic & medicinal chemistry, Mar-01, Volume: 16, Issue:5
| Structural insights into hydroxycoumarin-induced apoptosis in U-937 cells. |
| AID1441749 | Inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in presence of NA | | | |
| AID1441748 | Inhibition of full length recombinant human ALDH1A1 expressed in Escherichia coli BL21(DE3) assessed as remaining dehydrogenase activity by measuring NAD(P)H level at 10 uM preincubated for 2 mins followed by addition of propionaldehyde as substrate in pr | | | |
| AID977602 | Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID977599 | Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM | 2013 | Molecular pharmacology, Jun, Volume: 83, Issue:6
| Structure-based identification of OATP1B1/3 inhibitors. |
| AID1138893 | Antiasthamic activity in Wistar rat tracheal ring assessed as reversal of carbachol-induced contraction at 0.1 to 500 uM relative to control | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs. |
| AID1441753 | Lipophilicity, log P of the compound | | | |
| AID1138894 | Antiasthamic activity in Wistar rat tracheal ring assessed as reversal of carbachol-induced contraction | 2014 | European journal of medicinal chemistry, Apr-22, Volume: 77 | Semisynthesis, ex vivo evaluation, and SAR studies of coumarin derivatives as potential antiasthmatic drugs. |
| AID1159607 | Screen for inhibitors of RMI FANCM (MM2) intereaction | 2016 | Journal of biomolecular screening, Jul, Volume: 21, Issue:6
| A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway. |
| AID1159550 | Human Phosphogluconate dehydrogenase (6PGD) Inhibitor Screening | 2015 | Nature cell biology, Nov, Volume: 17, Issue:11
| 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |