7-ketopyrazolo(4,3-d)pyrimidine: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 135460353 |
| SCHEMBL ID | 1437770 |
| SCHEMBL ID | 570694 |
| SCHEMBL ID | 12005970 |
| MeSH ID | M0088596 |
| Synonym |
|---|
| nsc79301 |
| 13877-55-9 |
| 7h-pyrazolo[4, 1,4-dihydro- |
| 7-hydroxypyrazolo[4,3-d]pyrimidine |
| 1h-pyrazolo[4,3-d]pyrimidin-7-ol |
| nsc-79301 |
| 7-hydroxy-pyrazolo[4,3-d]pyrimidine |
| 7HP , |
| 1TC1 |
| 1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one |
| AKOS006352066 |
| 1,4-dihydropyrazolo[4,3-d]pyrimidin-7-one |
| unii-l69p3n2evq |
| 7-hydroxypyrazolo(4,3-d)pyrimidine |
| 1h-pyrazolo(4,3-d)pyrimidine-7-one |
| l69p3n2evq , |
| 1h-pyrazolo(4,3-d)pyrimidin-7-ol |
| 7h-pyrazolo(4,3-d)pyrimidin-7-one, 1,4-dihydro- |
| nsc 79301 |
| 7-ketopyrazolo(4,3-d)pyrimidine |
| SCHEMBL1437770 |
| AKOS015919836 |
| 39464-16-9 |
| SCHEMBL570694 |
| 2,6-dihydro-7h-pyrazolo[4,3-d]pyrimidin-7-one |
| 7h-pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro- |
| 1,6-dihydro-7h-pyrazolo[4,3-d]pyrimidin-7-one |
| SCHEMBL12005970 |
| 1h,6h,7h-pyrazolo[4,3-d]pyrimidin-7-one |
| DTXSID60160775 |
| AKOS025396672 |
| J-519273 |
| CS-W005985 |
| mfcd08234378 |
| 2h-pyrazolo[4,3-d]pyrimidin-7(6h)-one |
| 1797409-86-9 |
| 7-hydroxy-pyrazolo [4,3-d]pyrimidine |
| 1,6-dihydropyrazolo[4,3-d]pyrimidin-7-one |
| 7-hydroxy-1h-pyrazolo[4,3-d]pyrimidine |
| 1h-pyrazolo[4,3-d]pyrimidin-7(6h)-one |
| FT-0741857 |
| 4h-pyrazolo[4,3-d]pyrimidin-7-ol |
| DS-10848 |
| AMY14077 |
| SB17715 |
| SY029524 |
| 1,4-dihydropyrazolo(4,3-d)pyrimidin-7-one |
| 1,6-dihydropyrazolo(4,3-d)pyrimidin-7-one |
| 6h-pyrazolo(4,3-d)pyrimidin-7-ol |
| 7h-pyrazolo(4,3-d)pyrimidin-7-one, 2,6-dihydro- |
| P12441 |
| Q27456729 |
| A886188 |
| CS-0498637 |
| PD183132 |
| F76248 |
| EN300-115411 |
| Z1198176380 |
| Protein | Taxonomy | Measurement | Average | Min (ref.) | Avg (ref.) | Max (ref.) | Bioassay(s) |
|---|---|---|---|---|---|---|---|
| Chain A, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE) | Trypanosoma cruzi | IC50 (µMol) | 2,000.0000 | 2,000.0000 | 2,000.0000 | 2,000.0000 | AID977608 |
| [prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023] | |||||||
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1811 | Experimentally measured binding affinity data derived from PDB | 1998 | Biochemistry, Oct-27, Volume: 37, Issue:43 | A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi. |
| AID977608 | Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB | 1998 | Biochemistry, Oct-27, Volume: 37, Issue:43 | A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||