Assay ID | Title | Year | Journal | Article |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588501 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Lethal Factor Protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588499 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain A protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Current protocols in cytometry, Oct, Volume: Chapter 13 | Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2006 | Cytometry. Part A : the journal of the International Society for Analytical Cytology, May, Volume: 69, Issue:5
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. |
AID588497 | High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set | 2010 | Assay and drug development technologies, Feb, Volume: 8, Issue:1
| High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors. |
AID504812 | Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID1745845 | Primary qHTS for Inhibitors of ATXN expression | | | |
AID504810 | Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign | 2010 | Endocrinology, Jul, Volume: 151, Issue:7
| A small molecule inverse agonist for the human thyroid-stimulating hormone receptor. |
AID651635 | Viability Counterscreen for Primary qHTS for Inhibitors of ATXN expression | | | |
AID78810 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in human ileocecal carcinoma HCT-8 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID152256 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in murine leukemia P-388 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID214013 | Inhibition of tubulin polymerization | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID214186 | Percentage inhibition of colchicine binding(1:1 ratio of inhibitor: colchicine) | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID83787 | Inhibition of in vitro cell growth which reduces cell growth to level at start of experiment in colon HT-29 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID94842 | Inhibition of in vitro cell growth which reduces cell growth to level at start of experiment in colon KM-20L2 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID83772 | Inhibition of in vitro cell growth which reduces cell growth to 50% of level at start of experiment in colon HT-29 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID79789 | Inhibition of in vitro cell growth which reduces cell growth to 50% of level at start of experiment in colon HCC2998 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID8850 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in human lung carcinoma A-549 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID46470 | Inhibition of in vitro cell growth which reduces cell growth to level at start of experiment in colon COLO-205 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID214185 | Percentage inhibition of colchicine binding(10:1 ratio of inhibitor: colchicine) | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID79796 | Inhibition of in vitro cell growth which reduces cell growth to level at start of experiment in colon HCC2998 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID95516 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in human epidermoid carcinoma KB cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID46467 | Inhibition of in vitro cell growth which reduces cell growth to 50% of level at start of experiment in colon COLO-205 cell line (<-4 in one experiment, >-4 in other experiment) | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID167040 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in human melanoma RPMI-7951 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID94841 | Inhibition of in vitro cell growth which reduces cell growth to 50% of level at start of experiment in colon KM-20L2 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID201301 | Inhibition of in vitro cell growth which reduces cell growth to level at start of experiment in CNS SF-539 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID94725 | Cytotoxicity in vitro expressed as 50% reduction in cell number after a 3-day incubation, in murine leukemia L-1210 cell line | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
AID201293 | Inhibition of in vitro cell growth which reduces cell growth to 50% of level at start of experiment in CNS SF-539 cell line(<-4 in one experiment, >-4 in other experiment) | 1993 | Journal of medicinal chemistry, Apr-30, Volume: 36, Issue:9
| Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |