Compounds > 7-chlorobenz(a)anthracene
Page last updated: 2024-12-07

7-chlorobenz(a)anthracene

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

7-chlorobenz(a)anthracene: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID88446
MeSH IDM0133719

Synonyms (15)

Synonym
7-chlorobenz(a)anthracene
brn 3294219
ccris 3878
benz(a)anthracene, 7-chloro-
10-chloro-1,2-benzanthracene
7-chlorobenzo[a]anthracene
unii-2ozt3q4q8d
2ozt3q4q8d ,
20268-52-4
7-chlorobenz[a]anthracene
7-chlorotetraphene
j35.520h ,
7-chlorobenzo(a)anthracene
DTXSID20174116
Q27255281

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" Cytotoxicity as assessed by the classic 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and neutral red assays showed a mild toxic effect in response to single or multiple dose exposure for up to 72 h, except for multiple dose exposure to BaA and 7-ClBaA (1 μM/d for 4 d) and single exposure to 10 μM BaA."( Integration of cellular and molecular endpoints to assess the toxicity of polycyclic aromatic hydrocarbons in HepG2 cell line.
Cardoso, AS; Jordao, L; Jose, S; M Antunes, AM; Morgado, PI; Wanke, R, 2017)		0.46
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (14.29)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.72

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.72 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.80 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.72)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
3-methylcholanthrene
Methylcholanthrene: A carcinogen that is often used in experimental cancer studies.. 3-methylcholanthrene : A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.		1.9810ortho- and peri-fused polycyclic arenearyl hydrocarbon receptor agonist;
carcinogenic agent
benzo(a)pyrene
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.. benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.		1.9810ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
benz(a)anthracene
benz(a)anthracene: 4 fused rings of which one is angular in contrast to the linear NAPHTHACENES. tetraphene : An angular ortho-fused polycyclic arene consisting of four fused benzene rings.		2.5220ortho-fused polycyclic arene;
tetraphenes
pyrene
pyrene: structure in Merck Index, 9th ed, #7746. pyrene : An ortho- and peri-fused polycyclic arene consisting of four fused benzene rings, resulting in a flat aromatic system.		2.1510ortho- and peri-fused polycyclic arenefluorescent probe;
persistent organic pollutant
1-chloropyrene
1-chloropyrene: structure given in first source		2.1510
7-bromobenzanthracene
[no description available]		2.6830
ConditionIndicatedRelationship StrengthStudiesTrials
Experimental Hepatoma
[description not available]		01.9910
Adenoma, Hepatocellular
[description not available]		01.9910
Hepatocellular Carcinoma
[description not available]		01.9910
Cancer of Liver
[description not available]		01.9910
Carcinoma, Hepatocellular
A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.		01.9910
Liver Neoplasms
Tumors or cancer of the LIVER.		01.9910