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7,7'-(carbonyl-bis(imino-n-methyl-4,2-pyrrolcarbonylimino(n-methyl-4,2-pyrrol)carbonylimino))-bis(1,3-naphthalenedisulfonic acid)

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

FCE 26644: inhibits binding of basic fibroblast growth factor, platelet-derived growth factor beta and IL-7 to their receptors; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID132977
MeSH IDM0227431

Synonyms (14)

Synonym
154788-16-6
unii-xfp1gr4jyu
xfp1gr4jyu ,
pnu 145156e
7,7'-(carbonyl-bis(imino-n-methyl-4,2-pyrrolcarbonylimino(n-methyl-4,2-pyrrol)carbonylimino))-bis(1,3-naphthalenedisulfonic acid)
1,3-naphthalenedisulfonic acid, 7,7'-(carbonylbis(imino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino(1-methyl-1h-pyrrole-4,2-diyl)carbonylimino))bis-, tetrasodium salt
fce 26644
fce-26644
DTXSID90165718
sodium 7,7'-((4,4'-((4,4'-(carbonylbis(azanediyl))bis(1-methyl-1h-pyrrole-4,2-diyl-2-carbonyl))bis(azanediyl))bis(1-methyl-1h-pyrrole-4,2-diyl-2-carbonyl))bis(azanediyl))bis(naphthalene-1,3-disulfonate)
pnu-145156e (fce26644)
pnu 151484
pnu-151484
tetrasodium;7-[[4-[[4-[[5-[[5-[(6,8-disulfonatonaphthalen-2-yl)carbamoyl]-1-methylpyrrol-3-yl]carbamoyl]-1-methylpyrrol-3-yl]carbamoylamino]-1-methylpyrrole-2-carbonyl]amino]-1-methylpyrrole-2-carbonyl]amino]naphthalene-1,3-disulfonate

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
" Plasma and urine PNU-145156E was measured for pharmacokinetic analysis."( PNU-145156E, a novel angiogenesis inhibitor, in patients with solid tumors: a phase I and pharmacokinetic study.
de Vries, EG; Dirix, LY; Fokkema, E; Groen, HJ; Lechuga, MJ; Poggesi, I; van der Graaf, WT; van Oosterom, AT; Wynendaele, W, 2001
)
0.31
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's8 (80.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.63

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.63 (24.57)
Research Supply Index2.56 (2.92)
Research Growth Index4.20 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.63)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (9.09%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (90.91%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]